TMEM45B and C3orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM45B	C3orf52
Description		transmembrane protein 45B	chromosome 3 open reading frame 52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Membrane	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune System Process Innate Immune Response Response To Pain
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 22383897) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Obsessive-compulsive traits ( 33531474) Serum metabolite levels ( 33031748) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Type 2 diabetes ( 22238593)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		41 interacting genes: ANKRD46 APOD APOL2 AQP1 ARLN BMP10 C3orf52 CACNG1 CDS2 CYB561D2 DOLK FAM3C FKBP8 GIMAP1 INSIG2 LAT NSG1 PLN PLP1 PLPP4 SEC22A SEC23A SMAGP SMIM1 SNORC SYNGR1 TINAG TMEM128 TMEM218 TMEM229B TMEM243 TMEM254 TMEM60 TMEM97 TNFRSF10C TREX1 TSPAN33 UBE2G2 UPK1B VAMP5 VKORC1	74 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FKBP7 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB GPX8 HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SLC10A1 SLC10A2 SLC10A6 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 UPK2 ZNRF3
Entrez ID		120224	79669
HPRD ID		14020	08018
Ensembl ID		ENSG00000151715	ENSG00000114529
Uniprot IDs		Q96B21	Q5BVD1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Membrane Protein Binding Bile Acid:sodium Symporter Activity Plasma Membrane Glutathione Peroxidase Activity Bile Acid And Bile Salt Transport Leukotriene-C4 Synthase Activity
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