TMEM45B and TINAG

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TMEM45B	TINAG
Gene Name		transmembrane protein 45B	tubulointerstitial nephritis antigen
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Basement Membrane
	Molecular Function		Nucleotide Binding Cysteine-type Endopeptidase Activity Scavenger Receptor Activity Polysaccharide Binding
	Biological Process		Proteolysis Receptor-mediated Endocytosis Immune Response Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 22383897) Obesity-related traits ( 23251661) Type 2 diabetes ( 22238593)	Radiation response ( 20923822)
Protein-Protein Interactions		3 interactors: TINAG UBE2G2 VKORC1	3 interactors: CPB2 TERF1 TMEM45B
Entrez ID		120224	27283
HPRD ID		14020	09483
Ensembl ID		ENSG00000151715	ENSG00000137251
Uniprot IDs		Q96B21	Q6NSC1 Q9UJW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Vitamin K Metabolic Process Peptidyl-glutamic Acid Carboxylation Peptidyl-amino Acid Modification Protein K48-linked Ubiquitination Quinone Metabolic Process Drug Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process	Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Extracellular Matrix Constituent Secretion Negative Regulation Of Protein Processing Regulation Of Protein Processing Telomere Maintenance Via Telomere Shortening Negative Regulation Of Hepatocyte Proliferation Liver Regeneration Negative Regulation Of Telomere Maintenance Via Telomerase Response To Drug Negative Regulation Of Plasminogen Activation Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Fibrinolysis Regulation Of Telomere Maintenance Via Telomerase Regulation Of Hepatocyte Proliferation Positive Regulation Of Microtubule Polymerization Regulation Of Fibrinolysis Regulation Of Telomerase Activity Negative Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Fibrinolysis Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Blood Coagulation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Extracellular Matrix Organization Mitotic Spindle Checkpoint Positive Regulation Of Coagulation Positive Regulation Of Mitotic Nuclear Division Homeostatic Process Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Wound Healing Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Cellular Response To Glucose Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?			4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Difference) ?			4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Intersection) ?