CLK3 and OAS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK3	OAS2
Gene Name		CDC-like kinase 3	2-5-oligoadenylate synthetase 2, 69/71kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding ATP Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process RNA Catabolic Process Protein Glycosylation Response To Virus Protein Myristoylation Cytokine-mediated Signaling Pathway Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Response to fenofibrate (adiponectin levels) ( 23149075) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		19 interactors: APP CLK2 HOXB6 HOXB7 KRTAP10-3 NEDD4 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RSRP1 SDCBP SLAMF7 SRPK2 SUV39H1 TINF2 YWHAG ZNF263	2 interactors: APP CLK3
Entrez ID		1198	4939
HPRD ID		04290	04518
Ensembl ID		ENSG00000179335	ENSG00000111335
Uniprot IDs		B3KRI8 B3KTV2 P49761	P29728 Q7Z6D0
PDB IDs		2EU9 2EXE 2WU6 2WU7 3RAW
Enriched GO Terms of Interacting Partners?		MRNA Processing Regulation Of RNA Splicing MRNA Metabolic Process RNA Metabolic Process RNA Processing RNA Splicing Negative Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Gene Expression Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Immune System Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neuromuscular Junction Development Negative Regulation Of Protein ADP-ribosylation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Metabolic Process Cell Activation Regulation Of Cellular Process Cell Differentiation Cellular Component Assembly Ribonucleoprotein Complex Biogenesis Regulation Of Protein ADP-ribosylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Synaptic Growth At Neuromuscular Junction Immune Response Negative Regulation Of Gene Expression Regulation Of Synapse Structure Or Activity Innate Immune Response Collateral Sprouting In Absence Of Injury Positive Regulation Of Organelle Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Protein Glycosylation Protein Targeting Regulation Of Organelle Organization Histone Methylation	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Protein Phosphorylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Phosphorylation Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth Regulation Of RNA Splicing RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior
Tagcloud ?			abrogated aid antiviral cpg creates defense ecc epithelial estradiol ifnbeta imiquimod isg menstrual mounting mxa neutralizing peaked poly preceded restrictive sentinels slower tlr tlr3 uec unexpectedly upregulation uterine uterus
Tagcloud (Difference) ?			abrogated aid antiviral cpg creates defense ecc epithelial estradiol ifnbeta imiquimod isg menstrual mounting mxa neutralizing peaked poly preceded restrictive sentinels slower tlr tlr3 uec unexpectedly upregulation uterine uterus
Tagcloud (Intersection) ?