OAS2

Gene Name		2-5-oligoadenylate synthetase 2, 69/71kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding ATP Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process RNA Catabolic Process Protein Glycosylation Response To Virus Protein Myristoylation Cytokine-mediated Signaling Pathway Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-protein Interactions		2 interactors: APP CLK3
Entrez ID		4939
HPRD ID		04518
Ensembl ID		ENSG00000111335
Uniprot IDs		P29728 Q7Z6D0
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Protein Phosphorylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Phosphorylation Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth Regulation Of RNA Splicing RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior
Tagcloud ?		abrogated aid antiviral cpg creates defense ecc epithelial estradiol ifnbeta imiquimod isg menstrual mounting mxa neutralizing peaked poly preceded restrictive sentinels slower tlr tlr3 uec unexpectedly upregulation uterine uterus