GALNT15 and TMEM179B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GALNT15	TMEM179B
Description		polypeptide N-acetylgalactosaminyltransferase 15	transmembrane protein 179B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Transport Vesicle	Nucleolus Plasma Membrane Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine
Pathways		O-linked glycosylation of mucins	Neutrophil degranulation
Drugs
Diseases
GWAS		Numerical cognitive ability ( 31620175) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: CD200R1 CD79A CISD2 EVI2B FCRL6 FFAR2 FNDC9 GOLM1 IL27RA MR1 MUC1 PDCD1LG2 PDZK1IP1 SLC30A2 SLC7A1 SPSB2 SYNPR TMEM179B	47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 SLC61A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1
Entrez ID		117248	374395
HPRD ID		13563	14186
Ensembl ID		ENSG00000131386	ENSG00000185475
Uniprot IDs		C9JGI4 Q4G146 Q8N3T1	G3V185 Q7Z7N9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane External Side Of Plasma Membrane Negative Regulation Of T Cell Migration Positive Regulation Of Immune System Process Regulation Of Immune System Process Negative Regulation Of Lymphocyte Migration Immune Response Positive Regulation Of Neutrophil Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Negative Regulation Of T Cell Extravasation Negative Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Negative Regulation Of Interleukin-6 Production Transmembrane Signaling Receptor Activity Negative Regulation Of Leukocyte Migration	Membrane Inorganic Anion Transport
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