GALNT15 and CD200R1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GALNT15	CD200R1
Description		polypeptide N-acetylgalactosaminyltransferase 15	CD200 receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Transport Vesicle	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Receptor Complex
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding	Protein Binding Immunoglobulin Receptor Activity Signaling Receptor Activity Glycosylated Region Protein Binding
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine	Signal Transduction Negative Regulation Of Interleukin-6 Production Heterotypic Cell-cell Adhesion Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Macrophage Migration Negative Regulation Of T Cell Migration
Pathways		O-linked glycosylation of mucins	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Numerical cognitive ability ( 31620175) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Asthma ( 32296059) Blood protein levels ( 30072576) Economic and political preferences ( 22566634) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neurological blood protein biomarker levels ( 31320639) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		18 interacting genes: CD200R1 CD79A CISD2 EVI2B FCRL6 FFAR2 FNDC9 GOLM1 IL27RA MR1 MUC1 PDCD1LG2 PDZK1IP1 SLC30A2 SLC7A1 SPSB2 SYNPR TMEM179B	9 interacting genes: ADIPOQ CD200 CLDN19 ERMP1 GALNT15 NINJ1 PTCH1 SFTPC SGTB
Entrez ID		117248	131450
HPRD ID		13563	09609
Ensembl ID		ENSG00000131386	ENSG00000163606
Uniprot IDs		C9JGI4 Q4G146 Q8N3T1	Q8TD46
PDB IDs			9GWT
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane External Side Of Plasma Membrane Negative Regulation Of T Cell Migration Positive Regulation Of Immune System Process Regulation Of Immune System Process Negative Regulation Of Lymphocyte Migration Immune Response Positive Regulation Of Neutrophil Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Negative Regulation Of T Cell Extravasation Negative Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Negative Regulation Of Interleukin-6 Production Transmembrane Signaling Receptor Activity Negative Regulation Of Leukocyte Migration	Negative Regulation Of Cell Population Proliferation Cell-cell Adhesion Mediator Activity Negative Regulation Of Cell Migration Heterotypic Cell-cell Adhesion Ferroptosis Neural Plate Axis Specification Positive Regulation Of Cholesterol Efflux Regulation Of Cholesterol Transport Regulation Of Cholesterol Efflux Positive Regulation Of Cholesterol Transport Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Inflammatory Response Response To Chlorate Positive Regulation Of Lipid Transport Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Detection Of Oxidative Stress TRC Complex Mesaxon Regulation Of Cell Motility Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Locomotion Glycosylated Region Protein Binding Hedgehog Family Protein Binding Hedgehog Receptor Activity Response To Linoleic Acid Positive Regulation Of CAMP-dependent Protein Kinase Activity Negative Regulation Of Cholesterol Import Cell-cell Adhesion Protein Binding Involved In Heterotypic Cell-cell Adhesion Negative Regulation Of Protein Transport Regeneration Membrane Destabilizing Activity Epidermal Cell Fate Specification Smoothened Binding Localization Within Membrane Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Receptor Binding Regulation Of Glycogen (starch) Synthase Activity Regulation Of Transepithelial Transport Negative Regulation Of Establishment Of Protein Localization Regulation Of Lipid Transport Regulation Of Mononuclear Cell Migration Negative Regulation Of Secretion By Cell Regulation Of Cholesterol Import
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