FTSJ3 and OAS3

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (affinity chromatography technology, pull down)

		FTSJ3	OAS3
Gene Name		FtsJ homolog 3 (E. coli)	2-5-oligoadenylate synthetase 3, 100kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Preribosome, Small Subunit Precursor	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding RRNA Methyltransferase Activity Poly(A) RNA Binding	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Enzyme-directed RRNA 2'-O-methylation	Nucleobase-containing Compound Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Alcohol consumption ( 21270382) HDL cholesterol ( 21909109) Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		6 interactors: CSNK2A1 EIF2AK2 FANCG MAGEB4 OAS3 SAT1	5 interactors: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		117246	4940
HPRD ID		17024	04519
Ensembl ID		ENSG00000108592	ENSG00000111331
Uniprot IDs		Q8IY81	Q9Y6K5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Evasion Or Tolerance By Virus Of Host Immune Response Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spermidine Acetylation Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Viral Process Defense Response To Virus Cellular Nitrogen Compound Metabolic Process Regulation Of Ribonuclease Activity Evasion Or Tolerance Of Host Defenses By Virus Putrescine Catabolic Process Nitrogen Compound Metabolic Process Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation Cell Cycle Checkpoint Oxalate Transport Regulation Of Hematopoietic Stem Cell Proliferation Response To Virus Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Response To Host Immune Response Rhythmic Process Regulation Of NLRP3 Inflammasome Complex Assembly Cellular Response To Stimulus Regulation Of Cell Proliferation Regulation Of Translational Initiation In Response To Stress Negative Regulation Of Osteoblast Proliferation Neurotransmitter Uptake Modulation By Virus Of Host Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Regulation Of Translation In Response To Stress Response To Interferon-alpha Polyamine Biosynthetic Process Response To External Stimulus Modulation By Virus Of Host Morphology Or Physiology Response To Stimulus Amine Biosynthetic Process Regulation Of Osteoblast Proliferation Regulation Of Defense Response To Virus By Virus Negative Regulation Of Defense Response To Virus Regulation Of Hematopoietic Progenitor Cell Differentiation Polyamine Metabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Sulfate Transmembrane Transport Mitotic Spindle Checkpoint Response To Cytokine Sulfate Transport	Positive Regulation Of IP-10 Production Enzyme-directed RRNA 2'-O-methylation Ribosome Biogenesis Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production RIG-I Signaling Pathway Regulation Of Peroxisome Organization Mature Ribosome Assembly Cytoplasmic Pattern Recognition Receptor Signaling Pathway In Response To Virus Ribonucleoprotein Complex Biogenesis Cellular Response To Exogenous DsRNA Ribosomal Subunit Export From Nucleus Positive Regulation Of Protein Import Into Nucleus, Translocation RRNA Methylation Positive Regulation Of Type I Interferon-mediated Signaling Pathway RRNA Modification Cellular Response To Virus Positive Regulation Of Defense Response To Virus By Host Regulation Of Protein Import Into Nucleus, Translocation Positive Regulation Of Interferon-alpha Production Ribosomal Large Subunit Biogenesis Positive Regulation Of Interferon-beta Production Ribosome Assembly Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Defense Response To Virus By Host Positive Regulation Of Interleukin-8 Production Cellular Response To DsRNA Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of Interferon-beta Production Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Chemokine Production Negative Regulation Of Type I Interferon Production Negative Regulation Of Viral Genome Replication Response To Exogenous DsRNA Regulation Of Chemokine Production Positive Regulation Of Tumor Necrosis Factor Production RNA Methylation
Tagcloud ?			5as activate agrees antiviral baculovirus capability compelling considerably contrary dsrna harbors homogeneity intracellularly messengers mutagenesis oas1 oligoadenylate oligoadenylates purify redefines restrict rnase saxs scattering sensors synthesize synthesizes synthetase
Tagcloud (Difference) ?			5as activate agrees antiviral baculovirus capability compelling considerably contrary dsrna harbors homogeneity intracellularly messengers mutagenesis oas1 oligoadenylate oligoadenylates purify redefines restrict rnase saxs scattering sensors synthesize synthesizes synthetase
Tagcloud (Intersection) ?