PLAAT5 and HOMER3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLAAT5	HOMER3
Description		phospholipase A and acyltransferase 5	homer scaffold protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite Basal Part Of Cell Synapse Glutamatergic Synapse
	Molecular Function	Phospholipase A2 Activity Protein Binding Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity	Protein Binding Protein Domain Specific Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process N-acylphosphatidylethanolamine Metabolic Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		Acyl chain remodelling of PE	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: - APP CLK1 GGACT GOLGA2 HOMER3	90 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPA CEBPB CFTR CWF19L2 DRC4 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FMR1 FXR1 FXR2 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SAXO4 SCNM1 SDCBP SHANK3 SLAIN1 SMR3B SNCA SNRPF SRPK2 TBC1D22B TOX2 TRPC1 TSC1 USP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655
Entrez ID		117245	9454
HPRD ID		13672	07270
Ensembl ID		ENSG00000168004	ENSG00000051128
Uniprot IDs		B4DY88 Q8NE88 Q96KN8	Q9NSC5
PDB IDs			2P8V 3CVF
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Glutamate Receptor Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization G Protein-coupled Glutamate Receptor Binding Gamma-glutamylaminecyclotransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Protein Glycosylation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Protein Homooligomerization NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Golgi Disassembly Axon Choice Point Recognition Regulation Of Calcium Ion Transport Regulation Of Protein Glycosylation Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Protein Complex Oligomerization Cellular Response To Manganese Ion Importin-alpha Family Protein Binding Golgi Ribbon Formation Negative Regulation Of Blood Circulation	Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Dendritic Spine Cytoplasm Postsynapse Actin-based Cell Projection Postsynaptic Density SCAR Complex C/EBP Complex HMG Box Domain Binding Signaling Adaptor Activity Neuron Projection Growth Cone Filopodium CHOP-C/EBP Complex Cytoplasmic Ribonucleoprotein Granule Filopodium Tip Growth Cone Regulation Of Synaptic Plasticity Translation Regulator Activity Protein Tetramerization Glutamate Receptor Signaling Pathway Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Neurogenesis Cytoskeleton Cytoskeletal Anchor Activity Regulation Of Cytosolic Calcium Ion Concentration RNA Strand Annealing Activity Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Synapse Organization Telencephalon Regionalization Dorsal/ventral Pattern Formation Regulation Of Nervous System Process Regulation Of Cytoskeleton Organization Regulation Of Nervous System Development Intracellular Membraneless Organelle Scaffold Protein Binding Negative Regulation Of Centriole Replication Positive Regulation Of Nervous System Development Regulation Of Synaptic Transmission, Glutamatergic 14-3-3 Protein Binding RNA Splicing Regulation Of Neurogenesis MRNA Splicing, Via Spliceosome Proteasome Core Complex, Alpha-subunit Complex Neuron Spine Regulation Of Cell Projection Organization Developmental Maturation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?