CNTROB and KRABD2

		CNTROB	KRABD2
Description		centrobin, centriole duplication and spindle assembly protein	KRAB domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body
	Molecular Function	Protein Binding Protein Domain Specific Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process	Regulation Of DNA-templated Transcription DNA Integration
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23	1 interacting genes: HDAC7
Entrez ID		116840	124751
HPRD ID		13991	14028
Ensembl ID		ENSG00000170037	ENSG00000184619
Uniprot IDs		Q8N137	A8MX02 Q6ZNG9
PDB IDs
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity	Histone Deacetylase Activity Macromolecule Deacylation Negative Regulation Of Non-canonical NF-kappaB Signal Transduction 14-3-3 Protein Binding Protein Deacetylation SUMO Transferase Activity Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Protein Lysine Deacetylase Activity Membraneless Organelle Assembly Negative Regulation Of Interleukin-2 Production Histone Deacetylase Activity, Hydrolytic Mechanism Cellular Component Assembly Organelle Assembly Mitotic Cytokinetic Process Centriole Assembly Centriole Replication Microtubule-based Process Centrosome Separation Inner Dynein Arm 9+2 Motile Cilium Dynein Intermediate Chain Binding Axonemal Dynein Complex Assembly Minus-end-directed Microtubule Motor Activity Inner Dynein Arm Assembly Dynein Light Intermediate Chain Binding Axonemal Dynein Complex Dynein Complex Cytokinetic Process Histone Deacetylase Complex Protein Kinase C Binding Protein Sumoylation Regulation Of Cell Migration Involved In Sprouting Angiogenesis
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