RAB39B and RAB3GAP1

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		RAB39B	RAB3GAP1
Gene Name		RAB39B, member RAS oncogene family	RAB3 GTPase activating protein subunit 1 (catalytic)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Golgi Apparatus Plasma Membrane Vesicle Neuron Projection	Cytoplasm Protein Complex Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Rab GTPase Activator Activity Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Synapse Organization	Brain Development Hypothalamus Development Positive Regulation Of Rab GTPase Activity Lipid Particle Organization Camera-type Eye Development Regulation Of GTPase Activity Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Excitatory Postsynaptic Membrane Potential Face Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS			Cholesterol, total ( 20686565) Corneal structure ( 21979947)
Protein-Protein Interactions		5 interactors: GOLGA2 RAB3GAP1 RUFY1 SGSM3 ZDHHC17	8 interactors: FEZ1 FEZ2 RAB22A RAB39A RAB39B RAB3GAP2 RPH3AL WDR7
Entrez ID		116442	22930
HPRD ID		06703	16002
Ensembl ID		ENSG00000155961	ENSG00000115839
Uniprot IDs		Q96DA2	B9A6J2 C9J837 Q15042
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Positive Regulation Of Glutamate Secretion Plasma Membrane To Endosome Transport Rap Protein Signal Transduction Establishment Of Protein Localization Positive Regulation Of Amino Acid Transport Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Glutamate Secretion Lipid Particle Organization Positive Regulation Of Ras GTPase Activity Positive Regulation Of Neurotransmitter Secretion Regulation Of Intracellular Signal Transduction Lipoprotein Transport Magnesium Ion Transport Protein Localization Regulation Of Ras GTPase Activity Hypothalamus Development Protein Palmitoylation Regulation Of Ras Protein Signal Transduction Face Morphogenesis Positive Regulation Of GTPase Activity Head Morphogenesis Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Face Development Negative Regulation Of Protein Binding Regulation Of Neuronal Synaptic Plasticity Body Morphogenesis Regulation Of Signal Transduction Regulation Of Neurotransmitter Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Positive Regulation Of Hydrolase Activity Regulation Of Signaling	Rab Protein Signal Transduction Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Ras Protein Signal Transduction Establishment Of Protein Localization Intracellular Transport Protein Localization Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Vesicle Size Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Phagosome-lysosome Fusion Transport Phagosome Acidification Negative Regulation Of Macroautophagy Phagolysosome Assembly Establishment Of Mitochondrion Localization Intracellular PH Reduction Axon Guidance PH Reduction
Tagcloud ?		adolescents cd9 cenpa centromere driving embryonal fetal germ gonocytes histology igcnu intratubular kras2 microarrays neoplasia neoplastic nodal pathogenetic podxl preinvasive preliminary rala seminoma seminomas sox2 testes testicular tgcts unclassified	acidic adaptor anchored binds catalytic compartment consists envelope ergic etc execute ff ffat golgi gtpase heterodimer motif phenylalanines potently recruit reduces substitution tail traffic vap vesicle
Tagcloud (Difference) ?		adolescents cd9 cenpa centromere driving embryonal fetal germ gonocytes histology igcnu intratubular kras2 microarrays neoplasia neoplastic nodal pathogenetic podxl preinvasive preliminary rala seminoma seminomas sox2 testes testicular tgcts unclassified	acidic adaptor anchored binds catalytic compartment consists envelope ergic etc execute ff ffat golgi gtpase heterodimer motif phenylalanines potently recruit reduces substitution tail traffic vap vesicle
Tagcloud (Intersection) ?