C8orf34 and MTUS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		C8orf34	MTUS2
Gene Name		chromosome 8 open reading frame 34	microtubule associated tumor suppressor candidate 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Centrosome Cytoplasmic Microtubule
	Molecular Function		Protein Binding Microtubule Binding Protein Homodimerization Activity
	Biological Process
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 21732829) Obesity-related traits ( 23251661) Response to irinotecan in non-small-cell lung cancer ( 22664479)	Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: MCM7 MTUS2 UBC	167 interactors: AEN AES AFF4 ALS2CR11 AQP1 ARNT2 BMP7 BYSL C14orf105 C19orf66 C1orf109 C1orf216 C20orf195 C21orf58 C8orf34 CATIP CATSPER1 CBX8 CCDC116 CCDC146 CCDC17 CCDC60 CCHCR1 CDC20B CDC73 CDK18 CDK5R1 CDKL3 CEP57L1 CEP95 CERK COG2 CREB5 CRY2 CTSZ CWF19L2 CXCL11 CXCL16 DCDC2B DCTN4 DLGAP5 DMRT3 DOCK2 DTNB FAM13C FAM161A FAM71E2 FAM74A4 FAM90A1 FBXL18 FBXO34 FCHSD2 GAL3ST2 GOLGA2P11 GTF2I GTPBP10 HAUS1 HCK HDAC4 HSF2 IQCE ITGB5 ITSN1 KAT5 KIF1A LENG1 LIMS2 LINC00636 LMO2 LNX1 LOC153684 LRR1 LYSMD1 MAGEA8 MARK4 MFAP1 MTMR6 NDEL1 NDOR1 NELFE NUBPL NUDT10 ODF1 PDE4DIP PIN1 PKP2 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRPF31 PSMA1 PTPMT1 RAB3IL1 RGS2 RHPN1 RIBC2 ROBO3 RPA1 RPL9 RTP5 SCEL SDCBP SELM SETD5 SH2D4A SH3RF2 SLC23A1 SLC25A6 SLIRP SMARCE1 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPG7 STK16 SYT6 TAF13 THAP7 TP53RK TRIM42 TSGA10IP TSHZ3 TXN2 USP2 WAC WDYHV1 ZBTB38 ZC2HC1C ZFC3H1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZNF136 ZNF20 ZNF224 ZNF232 ZNF250 ZNF3 ZNF329 ZNF337 ZNF410 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF490 ZNF572 ZNF581 ZNF587 ZNF599 ZNF607 ZNF624 ZNF655 ZNF670 ZNF785 ZNF844 ZSCAN12 ZSCAN26
Entrez ID		116328	23281
HPRD ID		18281	11108
Ensembl ID		ENSG00000165084
Uniprot IDs		Q49A92	J3KQA9 Q5JR59
PDB IDs
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To Growth Factor Stimulus Response To Growth Factor Mitotic Cell Cycle Process Viral Protein Processing Mitotic Cell Cycle DNA Unwinding Involved In DNA Replication Cellular Response To DNA Damage Stimulus Notch Receptor Processing Virion Assembly Cell Cycle Process DNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Epidermal Growth Factor Stimulus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Response To Epidermal Growth Factor DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Replication Initiation Regulation Of Phosphorylation Cellular Polysaccharide Biosynthetic Process Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway	RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Mitochondrion Morphogenesis Histone Ubiquitination T Cell Chemotaxis Histone H2B Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tight Junction Assembly Cellular Response To Lipid Axon Cargo Transport Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Transepithelial Transport Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Lymphocyte Chemotaxis Regulation Of Cell Cycle Process Negative Regulation Of Phosphatase Activity T Cell Migration
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