PHACTR3 and UBL5

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		PHACTR3	UBL5
Name		phosphatase and actin regulator 3	ubiquitin like 5
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix	Nucleus Nucleoplasm Cytoplasm Cajal Body
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding	Protein Binding Protein Tag Activity
	Biological Process	Actin Cytoskeleton Organization	MRNA Splicing, Via Spliceosome Protein Modification Process Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		None	mRNA Splicing - Major Pathway
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644 ) General cognitive ability ( 29844566 ) Intelligence (MTAG) ( 29326435 ) Refractive error ( 32231278 ) Rheumatoid arthritis ( 30891314 ) Schizophrenia ( 30285260 )	Sleep duration ( 30531941 ) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010 )
Interacting Genes		10 interacting genes: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5	49 interacting genes: BEND7 BIN3 C1QTNF1 CCDC196 CCDC28B CERCAM CLK1 CLK2 CLK4 CTAG1A CTAG1B DMRTB1 FAM50B FANCI GCSAML HESX1 HID1 HMGXB4 HOXA1 HSPB2 KRTAP10-8 KRTAP13-3 LENG1 MBD3L1 NCOA5 NFYA NME4 NRIP3 PAX4 PHACTR3 PINX1 PRMT8 PSME2 SART1 SEPTIN2 SERTAD3 SF1 SMCP SPANXB1 SPATC1L TEX35 THAP3 TLE5 TRIM27 TRIM39 WASHC1 ZFP41 ZNF124 ZNF618
Entrez ID		116154	59286
HPRD ID		10571	06028
Ensembl ID		ENSG00000087495	ENSG00000198258
Uniprot IDs		B7Z339 Q96KR7	A0A024R7B0 Q9BZL1
PDB IDs		Not available	1P0R 4PYU 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9
GO Terms Enriched among Interactors		PTW/PP1 Phosphatase Complex Protein Serine/threonine Phosphatase Activity Dephosphorylation Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Glycogen Metabolic Process Myosin-light-chain-phosphatase Activity Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Protein Dephosphorylation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Septin Cytoskeleton Protein Modification Process Lung Development Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Nitric-oxide Synthase Complex Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Regulation Of Circadian Rhythm Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Myosin Phosphatase Activity Endoplasmic Reticulum Membrane Calpain Complex Protein Metabolic Process Phosphoprotein Phosphatase Activity Circadian Rhythm Nitrite Reductase (NO-forming) Activity Lipid Phosphatase Activity Glycogen Granule Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Menaquinone Metabolic Process Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Mitogen-activated Protein Kinase P38 Binding Lysophosphatidic Acid Phosphatase Activity RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Chromosome, Telomeric Region Positive Regulation Of CGAS/STING Signaling Pathway Energy Derivation By Oxidation Of Organic Compounds Double-strand Break Repair Via Alternative Nonhomologous End Joining	Identical Protein Binding Protein Serine/threonine/tyrosine Kinase Activity