PHACTR3

Name	phosphatase and actin regulator 3
Structure	No pdb structure
Interactors	10 interactors: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Actin Cytoskeleton Organization
GWAS	Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644 ) General cognitive ability ( 29844566 ) Intelligence (MTAG) ( 29326435 ) Refractive error ( 32231278 ) Rheumatoid arthritis ( 30891314 ) Schizophrenia ( 30285260 )
Entrez ID	116154
HPRD ID	10571
Ensembl ID	ENSG00000087495
Uniprot IDs	B7Z339 Q96KR7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	PTW/PP1 Phosphatase Complex Protein Serine/threonine Phosphatase Activity Dephosphorylation Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Glycogen Metabolic Process Myosin-light-chain-phosphatase Activity Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Protein Dephosphorylation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Septin Cytoskeleton Protein Modification Process Lung Development Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Nitric-oxide Synthase Complex Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Regulation Of Circadian Rhythm Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Myosin Phosphatase Activity Endoplasmic Reticulum Membrane Calpain Complex Protein Metabolic Process Phosphoprotein Phosphatase Activity Circadian Rhythm Nitrite Reductase (NO-forming) Activity Lipid Phosphatase Activity Glycogen Granule Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Menaquinone Metabolic Process Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Mitogen-activated Protein Kinase P38 Binding Lysophosphatidic Acid Phosphatase Activity RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Chromosome, Telomeric Region Positive Regulation Of CGAS/STING Signaling Pathway Energy Derivation By Oxidation Of Organic Compounds Double-strand Break Repair Via Alternative Nonhomologous End Joining