OTOP3 and SLC13A4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OTOP3	SLC13A4
Description		otopetrin 3	solute carrier family 13 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Proton Channel Activity Identical Protein Binding	Protein Binding Symporter Activity Solute:sodium Symporter Activity Sodium:sulfate Symporter Activity Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Ion Transmembrane Transport Proton Transmembrane Transport	Monoatomic Ion Transport Sodium Ion Transport Sodium Ion Transmembrane Transport Transmembrane Transport Sulfate Transmembrane Transport
Pathways			Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Iron status biomarkers (ferritin levels) ( 33536631)	Alcoholic chronic pancreatitis ( 28754779) Diverticular disease ( 30177863)
Interacting Genes		8 interacting genes: COMT EBP FAM210B SLC10A1 SLC13A4 TMEM237 TMEM31 ZFYVE27	26 interacting genes: ACKR2 CBLIF CD79A CDS1 CERS4 DEFB108B DERL3 EFNA5 EOGT ERMP1 FCER1G GJA5 GPR152 GPR61 IER3 IGFBP5 MS4A13 OPRD1 OTOP3 SLC35A4 SLC35E4 SLC38A1 SLC41A1 TMEM147 TMEM60 TRARG1
Entrez ID		347741	26266
HPRD ID		09700	10372
Ensembl ID		ENSG00000182938	ENSG00000164707
Uniprot IDs		Q7RTS5	A0A804HKQ4 Q59HF0 Q9UKG4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Phosphate Starvation Norepinephrine Secretion Catechol O-methyltransferase Activity Membrane Symporter Activity C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Sodium:sulfate Symporter Activity Habituation Mastication Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity O-methyltransferase Activity Dopamine Secretion Renal Protein Absorption Catecholamine Catabolic Process Norepinephrine Transport Nonassociative Learning Response To Dopamine Dopamine Catabolic Process Organic Hydroxy Compound Transport Catecholamine Secretion Cerebellar Cortex Morphogenesis Bile Acid Transmembrane Transporter Activity Bile Acid:sodium Symporter Activity Sodium Ion Transport Ossification Involved In Bone Maturation Cone Photoreceptor Outer Segment Rod Photoreceptor Outer Segment Endoplasmic Reticulum Tubular Network Formation Growth Cone Membrane Renal Tubular Secretion Cellular Response To Cocaine	Membrane
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