TNFRSF13C and TNFSF13B

Number of citations of the paper that reports this interaction (PMID 11509692)
139

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF13C	TNFSF13B
Gene Name		tumor necrosis factor receptor superfamily, member 13C	tumor necrosis factor (ligand) superfamily, member 13b
Image
Gene Ontology Annotations	Cellular Component	External Side Of Plasma Membrane Integral Component Of Membrane	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function		Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Immunoglobulin Secretion
Pathways
Drugs			1,4-Diethylene Dioxide Citric Acid Belimumab
Diseases
GWAS
Protein-Protein Interactions		2 interactors: TNFSF13B TRAF3	5 interactors: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		115650	10673
HPRD ID		05883	04914
Ensembl ID		ENSG00000159958	ENSG00000102524
Uniprot IDs		Q5H8V1 Q96RJ3	Q9Y275
PDB IDs		1MPV 1OQE 1OSX 1P0T 2HFG	1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 1OTZ 3V56
Enriched GO Terms of Interacting Partners?		B Cell Costimulation Immunoglobulin Secretion Positive Regulation Of Germinal Center Formation Positive Regulation Of Immune Response Toll Signaling Pathway Regulation Of Germinal Center Formation Regulation Of Immune Response Positive Regulation Of Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Immune Response Regulation Of Immune System Process B Cell Homeostasis Regulation Of Interferon-beta Production Positive Regulation Of B Cell Proliferation Negative Regulation Of Type I Interferon Production Regulation Of B Cell Proliferation Negative Regulation Of NF-kappaB Transcription Factor Activity Immunoglobulin Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Lymphocyte Homeostasis Positive Regulation Of B Cell Activation T Cell Costimulation Regulation Of Defense Response To Virus Toll-like Receptor 4 Signaling Pathway Positive Regulation Of T Cell Proliferation Leukocyte Homeostasis Cellular Response To Tumor Necrosis Factor Immune System Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Mononuclear Cell Proliferation Protein Secretion Response To Tumor Necrosis Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of T Cell Proliferation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Innate Immune Response Regulation Of Adaptive Immune Response Negative Regulation Of Cytokine Production Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Homeostasis Of Number Of Cells Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response	Positive Regulation Of Germinal Center Formation Regulation Of Germinal Center Formation Immune System Process B Cell Homeostasis Regulation Of Lymphocyte Activation Regulation Of B Cell Proliferation Regulation Of Cell Activation Lymphocyte Homeostasis Positive Regulation Of B Cell Activation Leukocyte Homeostasis Positive Regulation Of Adaptive Immune Response Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury B Cell Costimulation Regulation Of Adaptive Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Immunoglobulin Production In Mucosal Tissue Homeostasis Of Number Of Cells Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Isotype Switching To IgA Isotypes Axon Choice Point Recognition Regulation Of Immune System Process Positive Regulation Of Cell Activation Homeostatic Process Neuron Remodeling Regulation Of Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of B Cell Proliferation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Isotype Switching Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mucosal Immune Response Regulation Of Isotype Switching Positive Regulation Of Immune Response Mating Behavior Positive Regulation Of Immunoglobulin Mediated Immune Response Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of Immunoglobulin Production Negative Regulation Of B Cell Activation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response
Tagcloud ?		activating adjacent baff cascades correlates document encodes encoding germline his159tyr hodgkin immunoglobulin kappab1 kappab2 lymphoma modulate motif mutation recruitment requirement reveals subset substitution tail traf2 traf3 traf6 wt	17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv
Tagcloud (Difference) ?		activating adjacent baff cascades correlates document encodes encoding germline his159tyr hodgkin immunoglobulin kappab1 kappab2 lymphoma modulate motif mutation recruitment requirement reveals subset substitution tail traf2 traf3 traf6 wt	17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv
Tagcloud (Intersection) ?