TNFRSF13C and TNFSF13B

Number of citations of the paper that reports this interaction (PubMedID 12721620)
0

Data Source:
HPRD (in vitro, in vivo)

		TNFRSF13C	TNFSF13B
Description		TNF receptor superfamily member 13C	TNF superfamily member 13b
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Activity	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation	B Cell Homeostasis Lymphocyte Homeostasis Transitional One Stage B Cell Differentiation Immune System Process Germinal Center Formation Positive Regulation Of Germinal Center Formation Immune Response Cell Communication Signal Transduction Signaling B Cell Differentiation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation B Cell Proliferation Positive Regulation Of T Cell Proliferation Skin Development Regulation Of Immune Response
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs			1,4-Dioxane Belimumab
Diseases		Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Processed meat consumption ( 32066663) Schizophrenia ( 25056061 29483656)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32203549) IgG levels ( 28628107) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Spleen volume ( 34128465) Tonsillectomy ( 28928442 27182965) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)
Interacting Genes		2 interacting genes: TNFSF13B TRAF3	5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		115650	10673
HPRD ID		05883	04914
Ensembl ID		ENSG00000159958	ENSG00000102524
Uniprot IDs		Q5H8V1 Q96RJ3	A0A0U5J7Q1 Q9Y275
PDB IDs		1MPV 1OQE 1OSX 2HFG 3V56 4V46	1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN
Enriched GO Terms of Interacting Partners?		Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway B Cell Costimulation Positive Regulation Of Germinal Center Formation Transitional One Stage B Cell Differentiation Cytokine-mediated Signaling Pathway Toll Signaling Pathway Thioesterase Binding CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Germinal Center Formation Regulation Of Germinal Center Formation Immature B Cell Differentiation Positive Regulation Of Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Serine/threonine Protein Kinase Complex Regulation Of Immune Response Positive Regulation Of Immune System Process B Cell Homeostasis Immune Response Cell Surface Toll-like Receptor Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Toll-like Receptor 4 Signaling Pathway T Cell Costimulation Positive Regulation Of B Cell Proliferation B Cell Proliferation Type I Interferon-mediated Signaling Pathway Toll-like Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Skin Development MRNA Transcription Regulation Of Defense Response To Virus Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Interferon-beta Production Regulation Of B Cell Proliferation Lymphocyte Homeostasis Antiviral Innate Immune Response Interferon-mediated Signaling Pathway Signaling Adaptor Activity Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process T Cell Proliferation Leukocyte Homeostasis Positive Regulation Of Multicellular Organismal Process Positive Regulation Of B Cell Activation Positive Regulation Of Type I Interferon Production	Lymphocyte Homeostasis Regulation Of B Cell Proliferation Leukocyte Homeostasis Immune Response Regulation Of B Cell Activation Regulation Of Cell Activation Homeostasis Of Number Of Cells Immune System Process Regulation Of Mononuclear Cell Proliferation Signaling Receptor Activity Regulation Of Leukocyte Proliferation Adaptive Immune Response Positive Regulation Of B Cell Proliferation Positive Regulation Of Cell Activation Tumor Necrosis Factor-mediated Signaling Pathway Homeostatic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Multicellular Organismal-level Homeostasis Regulation Of Lymphocyte Activation Positive Regulation Of B Cell Activation Regulation Of Immune System Process Regulation Of Cell Population Proliferation Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cell Surface Receptor Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation B Cell Costimulation Signal Transduction Positive Regulation Of Leukocyte Proliferation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?