TNFRSF13C

Description		TNF receptor superfamily member 13C
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Activity
	Biological Process	Adaptive Immune Response Immune System Process Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases		Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Processed meat consumption ( 32066663) Schizophrenia ( 25056061 29483656)
Interacting Genes		2 interacting genes: TNFSF13B TRAF3
Entrez ID		115650
HPRD ID		05883
Ensembl ID		ENSG00000159958
Uniprot IDs		Q5H8V1 Q96RJ3
PDB IDs		1MPV 1OQE 1OSX 2HFG 3V56 4V46
Enriched GO Terms of Interacting Partners?		Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway B Cell Costimulation Positive Regulation Of Germinal Center Formation Transitional One Stage B Cell Differentiation Cytokine-mediated Signaling Pathway Toll Signaling Pathway Thioesterase Binding CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Germinal Center Formation Regulation Of Germinal Center Formation Immature B Cell Differentiation Positive Regulation Of Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Serine/threonine Protein Kinase Complex Regulation Of Immune Response Positive Regulation Of Immune System Process B Cell Homeostasis Immune Response Cell Surface Toll-like Receptor Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Toll-like Receptor 4 Signaling Pathway T Cell Costimulation Positive Regulation Of B Cell Proliferation B Cell Proliferation Type I Interferon-mediated Signaling Pathway Toll-like Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Skin Development MRNA Transcription Regulation Of Defense Response To Virus Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Interferon-beta Production Regulation Of B Cell Proliferation Lymphocyte Homeostasis Antiviral Innate Immune Response Interferon-mediated Signaling Pathway Signaling Adaptor Activity Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process T Cell Proliferation Leukocyte Homeostasis Positive Regulation Of Multicellular Organismal Process Positive Regulation Of B Cell Activation Positive Regulation Of Type I Interferon Production
Tagcloud ?