MBD6 and DUSP12

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MBD6	DUSP12
Gene Name		methyl-CpG binding domain protein 6	dual specificity phosphatase 12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Chromocenter	Nucleus Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Kinase Binding
	Biological Process		Cellular Protein Modification Process Protein Dephosphorylation Positive Regulation Of Glucokinase Activity Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ATXN1L DUSP12	12 interactors: APP CALCOCO2 CCNH EIF5 HSPB8 KIAA1377 MBD6 NR1H2 PPP2R3B PTN RABAC1 USO1
Entrez ID		114785	11266
HPRD ID		11296	05323
Ensembl ID		ENSG00000166987	ENSG00000081721
Uniprot IDs		Q6P0P0 Q96DN6	Q9UNI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Glucokinase Activity	Mitotic Cell Cycle Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Synaptic Growth At Neuromuscular Junction Golgi Vesicle Docking Collateral Sprouting In Absence Of Injury Regulation Of High-density Lipoprotein Particle Assembly Learning Regulation Of Catalytic Activity Cell Cycle Negative Regulation Of Pinocytosis G1/S Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Axon Choice Point Recognition Intracellular Receptor Signaling Pathway Negative Regulation Of Cholesterol Storage Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Vesicle Fusion With Golgi Apparatus Positive Regulation Of Digestive System Process DNA-templated Transcription, Initiation Neuron Remodeling
Tagcloud ?			bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Difference) ?			bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Intersection) ?