MBD6

Description		methyl-CpG binding domain protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Chromosome Chromocenter
	Molecular Function	DNA Binding Chromatin Binding Protein Binding
	Biological Process
Pathways		UCH proteinases
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: ATXN1L DUSP12 NCK2 RBM10
Entrez ID		114785
HPRD ID		11296
Ensembl ID		ENSG00000166987
Uniprot IDs		Q6P0P0 Q96DN6
PDB IDs
Enriched GO Terms of Interacting Partners?		Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Smooth Muscle Cell Apoptotic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Ribosome Biogenesis Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress POZ Domain Binding Regulation Of Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Translation In Response To Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Smooth Muscle Cell Proliferation Signal Complex Assembly Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Cell Population Proliferation Immunological Synapse Formation Dendritic Spine Development Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Smooth Muscle Cell Apoptotic Process Muscle Cell Apoptotic Process Protein Tyrosine/serine/threonine Phosphatase Activity Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization Cytoskeletal Anchor Activity Regulation Of Translation In Response To Stress Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression MiRNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Biosynthetic Process Signaling Receptor Complex Adaptor Activity Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response
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