SYNPO and NONO

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SYNPO	NONO
Gene Name		synaptopodin	non-POU domain containing, octamer-binding
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Tight Junction Postsynaptic Density Actin Cytoskeleton Dendritic Spine Perikaryon Postsynaptic Membrane	Nucleus Nucleoplasm Nucleolus Membrane Nuclear Matrix Nuclear Speck Paraspeckles
	Molecular Function	Actin Binding Protein Binding	Nucleotide Binding Core Promoter Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly	DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: MAGI1 NCK1 NCK2 NONO YWHAG YWHAZ	35 interactors: APBB1 AR C11orf68 CA2 DDX6 ERG EWSR1 FXR2 HIST3H3 IL7R IRAK3 LMO4 MAD1L1 NUPR1 ORC5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 WBP4 YLPM1 ZNRD1
Entrez ID		11346	4841
HPRD ID		12179	02098
Ensembl ID		ENSG00000171992	ENSG00000147140
Uniprot IDs		Q8N3V7	Q15233
PDB IDs			3SDE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Phosphorylation Positive Regulation Of Organelle Organization Regulation Of Peptidyl-serine Phosphorylation Regulation Of Signal Transduction Signal Complex Assembly Regulation Of Signaling Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of Organelle Organization Lamellipodium Assembly Regulation Of Protein Phosphorylation Lamellipodium Organization Positive Regulation Of Mitochondrion Organization Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Leukocyte Activation Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Mitochondrion Organization Regulation Of Cell Death Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Cap-independent Translational Initiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Protein Polymerization Cell Activation Cellular Response To Stimulus Positive Regulation Of Translation In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Cytoplasmic Translation Cellular Component Assembly Regulation Of T Cell Proliferation Regulation Of Protein Kinase Activity Positive Regulation Of Transport	Regulation Of Gene Expression RNA Metabolic Process Gene Expression Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Nucleosome Disassembly Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Triglyceride Catabolic Process Rhythmic Process Photoperiodism Entrainment Of Circadian Clock Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Acylglycerol Catabolic Process Cell Cycle Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Chromatin Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Glycogen Catabolic Process Energy Reserve Metabolic Process Chromatin Organization Chromosome Organization Biosynthetic Process Regulation Of Cellular Process Glycogen Metabolic Process MRNA Metabolic Process RNA Splicing Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Cellular Component Organization Polysaccharide Metabolic Process
Tagcloud ?		appearances barely cxxc5 deg degs egfl7 exclusions exon fhl1 foxm1 gains hub inclusions ingenuity ipa maz multilateral ndrg2 pah phh plk1 rcan1 reads seq signatures suddenly tmpo transcriptomic ttll1	acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2
Tagcloud (Difference) ?		appearances barely cxxc5 deg degs egfl7 exclusions exon fhl1 foxm1 gains hub inclusions ingenuity ipa maz multilateral ndrg2 pah phh plk1 rcan1 reads seq signatures suddenly tmpo transcriptomic ttll1	acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2
Tagcloud (Intersection) ?