NRM and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NRM	KIR2DL3
Description		nurim	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane Nuclear Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process		Immune Response-regulating Signaling Pathway Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)
Interacting Genes		51 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35H1 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		11270	3804
HPRD ID		10120	10383
Ensembl ID		ENSG00000137404	ENSG00000243772
Uniprot IDs		A0A1U9X845 B3KQU6 Q8IXM6	E3NZD8 P43628
PDB IDs			1B6U 6PAG 8TUI
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Bile Acid:sodium Symporter Activity	Membrane Protein Binding Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cholesterol Binding CD27 Signaling Pathway
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