SPATA20 and ST6GALNAC4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SPATA20	ST6GALNAC4
Description		spermatogenesis associated 20	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function		Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process Spermatogenesis Cell Differentiation	Ganglioside Biosynthetic Process Protein Glycosylation Lipid Metabolic Process Glycolipid Metabolic Process Oligosaccharide Metabolic Process Protein O-linked Glycosylation Via N-acetyl-galactosamine Viral Protein Processing
Pathways			Sialic acid metabolism Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Hip index ( 34021172) Reticulocyte count ( 32888494) Triglyceride levels ( 32203549)	Body mass index ( 26426971)
Interacting Genes		3 interacting genes: CORO1A ST6GALNAC4 XRN1	1 interacting genes: SPATA20
Entrez ID		64847	27090
HPRD ID		07961	05902
Ensembl ID		ENSG00000006282	ENSG00000136840
Uniprot IDs		Q8TB22	A8K7N4 Q9H4F1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Puromycin Cellular Response To Cycloheximide Uropod Organization Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase Activity Phagolysosome Assembly Negative Regulation Of Vesicle Fusion Thymocyte Migration Early Endosome To Recycling Endosome Transport Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Response To Cycloheximide 5'-3' RNA Exonuclease Activity Natural Killer Cell Degranulation Myosin Heavy Chain Binding Negative Regulation Of Actin Nucleation G-quadruplex RNA Binding G-quadruplex DNA Binding 5'-3' Exonuclease Activity Nuclear MRNA Surveillance Ganglioside Biosynthetic Process Immunological Synapse Formation Nerve Growth Factor Signaling Pathway Histone MRNA Catabolic Process Phosphatidylinositol 3-kinase Binding Sialyltransferase Activity RRNA Catabolic Process Neurotrophin Signaling Pathway Negative Regulation Of Cellular Component Organization Positive Regulation Of T Cell Migration Regulation Of Vesicle Fusion T Cell Homeostasis Response To Interleukin-4 Phagocytic Cup Actin Monomer Binding T Cell Migration Epithelial Cell Migration Cellular Response To Interleukin-4 Regulation Of Actin Nucleation Glycosphingolipid Biosynthetic Process Ganglioside Metabolic Process Viral Protein Processing Protein O-linked Glycosylation Via N-acetyl-galactosamine Telomerase RNA Binding Negative Regulation Of Telomere Maintenance Via Telomerase Nuclear RNA Surveillance Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Histone MRNA Metabolic Process Leukocyte Degranulation Homeostasis Of Number Of Cells Within A Tissue Negative Regulation Of Telomere Maintenance
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