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SPATA20 and ST6GALNAC4
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SPATA20
ST6GALNAC4
Gene Name
spermatogenesis associated 20
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Golgi Membrane
Integral Component Of Membrane
Molecular Function
Catalytic Activity
Sialyltransferase Activity
(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase Activity
Biological Process
Multicellular Organismal Development
Spermatogenesis
Metabolic Process
Cell Differentiation
Dolichol-linked Oligosaccharide Biosynthetic Process
Protein O-linked Glycosylation
Glycolipid Metabolic Process
O-glycan Processing
Protein N-linked Glycosylation Via Asparagine
Post-translational Protein Modification
Cellular Protein Metabolic Process
Sialylation
Pathways
Diseases of glycosylation
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective MOGS causes MOGS-CDG (CDG-2b)
O-linked glycosylation
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective MAN1B1 causes MRT15
Defective ALG11 causes ALG11-CDG (CDG-1p)
Defective ALG2 causes ALG2-CDG (CDG-1i)
Defective ALG3 causes ALG3-CDG (CDG-1d)
Post-translational protein modification
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Termination of O-glycan biosynthesis
Synthesis of substrates in N-glycan biosythesis
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective RFT1 causes RFT1-CDG (CDG-1n)
Asparagine N-linked glycosylation
Defective ALG8 causes ALG8-CDG (CDG-1h)
Sialic acid metabolism
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Defective ALG12 causes ALG12-CDG (CDG-1g)
O-linked glycosylation of mucins
Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
CORO1A
ST6GALNAC4
XRN1
1 interactors:
SPATA20
Entrez ID
64847
27090
HPRD ID
07961
05902
Ensembl ID
ENSG00000006282
ENSG00000136840
Uniprot IDs
Q8TB22
A8K7N4
Q9H4F1
PDB IDs
Enriched GO Terms of Interacting Partners
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Early Endosome To Recycling Endosome Transport
Uropod Organization
Negative Regulation Of Vesicle Fusion
Nuclear MRNA Surveillance
RNA Surveillance
Phagolysosome Assembly
Histone MRNA Catabolic Process
Nerve Growth Factor Signaling Pathway
RRNA Catabolic Process
Negative Regulation Of Actin Nucleation
Histone MRNA Metabolic Process
Regulation Of Actin Nucleation
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Cellular Response To Nerve Growth Factor Stimulus
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Positive Chemotaxis
Regulation Of Vesicle Fusion
T Cell Homeostasis
Homeostasis Of Number Of Cells Within A Tissue
Phagosome Maturation
Cellular Response To Interleukin-4
O-glycan Processing
Response To Interleukin-4
Lysosome Organization
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Sialylation
Dolichol-linked Oligosaccharide Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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