EFNA3 and EPHA5

Number of citations of the paper that reports this interaction (PMID 10516308)
10

Data Source:
HPRD (in vivo)

		EFNA3	EPHA5
Gene Name		ephrin-A3	EPH receptor A5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane	Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Axon Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Transmembrane-ephrin Receptor Activity Ephrin Receptor Binding	Ephrin Receptor Activity GPI-linked Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding
	Biological Process	Cell-cell Signaling Axon Guidance Ephrin Receptor Signaling Pathway	Axon Guidance Peptidyl-tyrosine Phosphorylation CAMP-mediated Signaling Hippocampus Development Regulation Of Rac GTPase Activity Positive Regulation Of CREB Transcription Factor Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Neuron Development Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	HIV-1 viral setpoint ( 22174851)
Protein-Protein Interactions		9 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 KRTAP10-3 MEOX2 NOTCH2NL PRSS23	6 interactors: EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 NEDD4
Entrez ID		1944	2044
HPRD ID		03225	02474
Ensembl ID		ENSG00000143590	ENSG00000145242
Uniprot IDs		B7ZAD3 P52797	B7ZKJ3 B7ZKW7 F8VP57 F8W9W0 P54756 Q59FT4
PDB IDs			2R2P 4ET7
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Rho GTPase Activity Cell Morphogenesis Involved In Differentiation Neuron Projection Development Regulation Of Rho Protein Signal Transduction Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Regulation Of Rac GTPase Activity Regulation Of Ras GTPase Activity Locomotion Axonal Fasciculation Protein Phosphorylation Anatomical Structure Morphogenesis Regulation Of Ras Protein Signal Transduction Movement Of Cell Or Subcellular Component Regulation Of Rac Protein Signal Transduction Neuron Recognition Generation Of Neurons Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Neurogenesis Multicellular Organismal Development Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Cell Development Response To External Stimulus Phosphorylation Cell Differentiation Developmental Process Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity Notochord Cell Development Nervous System Development Regulation Of Cell Projection Organization Regulation Of Catalytic Activity	Ephrin Receptor Signaling Pathway Neuron Projection Development Neuron Development Axon Guidance Neuron Differentiation Cell Projection Organization Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Generation Of Neurons Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Cell Morphogenesis Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Cell Differentiation Response To External Stimulus Cell-cell Signaling System Development Osteoclast Differentiation Multicellular Organismal Development Anatomical Structure Development Bone Remodeling Signal Transduction Regulation Of Dendrite Morphogenesis Developmental Process Signaling Cell Communication Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Tissue Remodeling Myeloid Leukocyte Differentiation Cellular Response To Stimulus Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Dendritic Spine Morphogenesis Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Mesenchyme Development Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efnb2 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53	aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable
Tagcloud (Difference) ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efnb2 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53	aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable
Tagcloud (Intersection) ?