SLC27A2 and GEMIN5

Number of citations of the paper that reports this interaction (PubMedID 40355756)
172

Data Source:
BioGRID (affinity chromatography technology)

		SLC27A2	GEMIN5
Description		solute carrier family 27 member 2	gem nuclear organelle associated protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transmembrane Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Ligase Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Lipid Transport Bile Acid Metabolic Process Fatty Acid Transport Long-chain Fatty Acid Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Very Long-chain Fatty Acid Catabolic Process Long-chain Fatty Acid Import Into Cell Fatty-acyl-CoA Biosynthetic Process Methyl-branched Fatty Acid Metabolic Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Translation Regulation Of Translation RNA Splicing Protein-containing Complex Assembly
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Beta-oxidation of very long chain fatty acids Neutrophil degranulation Fatty acyl-CoA biosynthesis Peroxisomal protein import Peroxisomal protein import	snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Platelet count ( 32888494) Verbal declarative memory ( 25648963)	Venous thromboembolism ( 32232851)
Interacting Genes		4 interacting genes: ABCD1 PEX5 UBC YWHAQ	22 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNF10 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2
Entrez ID		11001	25929
HPRD ID		11935	06109
Ensembl ID		ENSG00000140284	ENSG00000082516
Uniprot IDs		O14975	B7ZLC9 Q58EZ8 Q8TEQ6
PDB IDs			5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS 7XDT 7XGR
Enriched GO Terms of Interacting Partners?		Protein Targeting	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Spliceosomal Complex Assembly U2 SnRNP Protein-RNA Complex Assembly U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Methylation Catalytic Step 2 Spliceosome Precatalytic Spliceosome Spliceosomal Complex Protein-containing Complex Assembly Macromolecule Methylation MRNA Metabolic Process Protein-containing Complex Organization SMN Complex Gemini Of Cajal Bodies RNA Modification RNA Processing MRNA Splicing, Via Spliceosome Methylation Spliceosomal Tri-snRNP Complex Cellular Component Assembly Ribonucleoprotein Complex RNA Metabolic Process Telomerase Holoenzyme Complex Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear Body Histone Pre-mRNA DCP Binding RNA Binding Commitment Complex U1 SnRNP Binding JNK Cascade Cytosol
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