ZNF490 and HOXB13

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZNF490	HOXB13
Description		zinc finger protein 490	homeobox B13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Morphogenesis Of An Epithelium Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Epidermis Development Response To Wounding Prostate Gland Development Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Prostate cancer ( 23104005 23535732)
Interacting Genes		35 interacting genes: CCDC136 CCNDBP1 CEP70 DTNBP1 FSD2 GLRX3 GOLGA6L9 HAP1 HOXB13 KRT40 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 LMNA LZTR1 LZTS2 MDFI MEOX2 MTUS2 NDEL1 RBMX RNPS1 STX1A TBX21 TEX19 TRAF1 TRIM41 TSGA10 VWC2 ZBTB32 ZC4H2 ZRANB1	7 interacting genes: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 ZNF490
Entrez ID		57474	10481
HPRD ID		15802	05210
Ensembl ID		ENSG00000188033	ENSG00000159184
Uniprot IDs		Q9ULM2	Q4KR72 Q92826
PDB IDs			2CRA 5EDN 5EEA 5EF6 5EG0 5EGO 5NO6 7PSX 8BYX
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Vesicle Transport Along Microtubule Vesicle Cytoskeletal Trafficking	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA Binding Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Pattern Specification Process Embryonic Skeletal System Morphogenesis Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Skeletal System Morphogenesis Positive Regulation Of Metabolic Process Hippocampal Neuron Apoptotic Process Animal Organ Morphogenesis Embryonic Organ Morphogenesis Regulation Of Macromolecule Metabolic Process Mediator Complex Binding Animal Organ Development Anterior/posterior Pattern Specification Cellular Response To Testosterone Stimulus Regulation Of Metabolic Process Cell Growth Involved In Cardiac Muscle Cell Development Plasma Membrane To Endosome Transport Cellular Developmental Process Transcription Regulator Activator Activity Nucleus Transcription Regulator Complex HMG Box Domain Binding Transcription Cis-regulatory Region Binding T-helper 17 Cell Lineage Commitment Regionalization Lens Morphogenesis In Camera-type Eye Positive Regulation Of Interleukin-13 Production
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