BLCAP and ASGR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BLCAP	ASGR1
Description		BLCAP apoptosis inducing factor	asialoglycoprotein receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Asialoglycoprotein Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Identical Protein Binding Fucose Binding Metal Ion Binding
	Biological Process	Apoptotic Process Apoptotic Nuclear Changes	Endocytosis Receptor-mediated Endocytosis Immune Response
Pathways			Asparagine N-linked glycosylation
Drugs			Von Willebrand factor human
Diseases
GWAS		Rheumatoid arthritis ( 30891314)	Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 22001757 33972514) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 29403010 31666285 33339817 33547301) Total cholesterol levels ( 33339817)
Interacting Genes		17 interacting genes: ASGR1 CLDND2 CYSRT1 FAM241B GIMAP1 GJA5 GOSR2 HOXA1 LEMD1 LRAT NOTCH2NLA SKAP1 SLC61A1 SSMEM1 TMEM14B TMEM237 TMEM31	44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 RBBP6 RNF19B SAR1A SLC10A1 SLC35H1 SNCA SPAG4 SUSD3 TG TMX2 VKORC1 VSIR
Entrez ID		10904	432
HPRD ID		16552	00151
Ensembl ID		ENSG00000166619	ENSG00000141505
Uniprot IDs		P62952	P07306 Q6FGQ5
PDB IDs			1DV8 5JPV 5JQ1 6YAU 8TS0
Enriched GO Terms of Interacting Partners?		Membrane Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Semicircular Canal Formation O-palmitoyltransferase Activity Phosphatidylcholine-retinol O-acyltransferase Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Asialoglycoprotein Receptor Activity Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Artery Morphogenesis Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Abducens Nerve Formation Optokinetic Behavior Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Renin Secretion Into Blood Stream Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Regulation Of AV Node Cell Action Potential Cerebral Cortex Development Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling	Membrane Nuclear Inner Membrane
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