YIF1A and HEATR1

		YIF1A	HEATR1
Description		Yip1 interacting factor homolog A, membrane trafficking protein	HEAT repeat containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Fibrillar Center Nucleus Nucleoplasm Nucleolus Mitochondrion Membrane 90S Preribosome Small-subunit Processome T-UTP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing RRNA Metabolic Process Ribosome Biogenesis Ribosomal Small Subunit Biogenesis Positive Regulation Of Transcription By RNA Polymerase I Neural Precursor Cell Proliferation Protein Localization To Nucleolus Positive Regulation Of RRNA Processing
Pathways		XBP1(S) activates chaperone genes	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	Post bronchodilator FEV1/FVC ratio ( 26634245) Total cholesterol levels ( 30275531)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	4 interacting genes: AAGAB RNF10 VPS52 XRN1
Entrez ID		10897	55127
HPRD ID		06755	10962
Ensembl ID		ENSG00000174851	ENSG00000119285
Uniprot IDs		A6NGW1 A8K509 O95070	A2VDI1 B2RWN5 Q9H583
PDB IDs			7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Embryonic Ectodermal Digestive Tract Development Cellular Response To Puromycin Cellular Response To Cycloheximide GARP Complex EARP Complex Ectodermal Cell Differentiation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Response To Cycloheximide 5'-3' RNA Exonuclease Activity Vesicle-mediated Cholesterol Transport Protein Transport Golgi Vesicle Transport Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation G-quadruplex RNA Binding G-quadruplex DNA Binding 5'-3' Exonuclease Activity Nuclear MRNA Surveillance Establishment Of Protein Localization Histone MRNA Catabolic Process Golgi To Vacuole Transport Embryonic Digestive Tract Development Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation RRNA Catabolic Process Intracellular Cholesterol Transport Negative Regulation Of Telomere Maintenance Via Telomerase Telomerase RNA Binding Intracellular Sterol Transport Histone MRNA Metabolic Process
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