PPP1R17 and PRKG1

Number of citations of the paper that reports this interaction (PMID 10051666)
7

Data Source:
HPRD (in vitro)

		PPP1R17	PRKG1
Gene Name		protein phosphatase 1, regulatory subunit 17	protein kinase, cGMP-dependent, type I
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Inhibitor Activity	CGMP-dependent Protein Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding CGMP Binding
	Biological Process	Central Nervous System Development Regulation Of Phosphatase Activity Intracellular Signal Transduction Negative Regulation Of Catalytic Activity	Neuron Migration Protein Phosphorylation Signal Transduction Blood Coagulation Dendrite Development CGMP-mediated Signaling Actin Cytoskeleton Organization Forebrain Development Regulation Of GTPase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Platelet Aggregation
Pathways			Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Asthma ( 21907864) Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: APP PRKACA PRKG1	34 interactors: ANXA7 CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 ITPR1 LASP1 LMO2 MRVI1 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPT3 SF1 SPP1 TBXA2R TNNT1 TRIM39-RPP21 TRPC3 VASP ZNF646
Entrez ID		10842	5592
HPRD ID		06820	08910
Ensembl ID		ENSG00000106341	ENSG00000185532
Uniprot IDs		O96001	Q13976
PDB IDs			1ZXA 3NMD 3OCP 3OD0 3OGJ
Enriched GO Terms of Interacting Partners?		Regulation Of Platelet Aggregation Regulation Of Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Regulation Of Blood Coagulation Positive Regulation Of Mitotic Cell Cycle Regulation Of Wound Healing Second-messenger-mediated Signaling Dendrite Development Regulation Of Protein Binding Cell Maturation Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Muscle Contraction Locomotion Protein Phosphorylation Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Regulation Of Binding Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Cell Development Calcium Ion Homeostasis Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Response To Light Stimulus Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cell-cell Adhesion Peptidyl-serine Autophosphorylation Axon Choice Point Recognition Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Processing Cellular Metal Ion Homeostasis Regulation Of Mitotic Cell Cycle Nervous System Development Cellular Cation Homeostasis Forebrain Development	Regulation Of Body Fluid Levels Hemostasis Regulation Of Muscle Contraction Blood Coagulation Negative Regulation Of Muscle Contraction Regulation Of Cardiac Muscle Hypertrophy Wound Healing Response To Wounding Cellular Response To Stimulus Response To Stimulus Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Process Response To Organic Substance Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Calcium Ion Homeostasis Relaxation Of Muscle Calcium Ion Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Blood Circulation Signal Transduction Cellular Chemical Homeostasis Regulation Of Phospholipase Activity Platelet Activation Ion Homeostasis Neurotrophin TRK Receptor Signaling Pathway Vasodilation Neurotrophin Signaling Pathway Cellular Metal Ion Homeostasis Signaling Cell Communication Muscle System Process Cellular Homeostasis Metal Ion Homeostasis Relaxation Of Vascular Smooth Muscle Activation Of Phospholipase C Activity Positive Regulation Of Metabolic Process Regulation Of Smooth Muscle Contraction Relaxation Of Smooth Muscle Positive Regulation Of Phospholipase C Activity Regulation Of Ion Homeostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Purine-containing Compound Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Cellular Response To Fibroblast Growth Factor Stimulus Relaxation Of Cardiac Muscle
Tagcloud ?			1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Difference) ?			1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Intersection) ?