CEACAM3 and CEACAM1

Number of citations of the paper that reports this interaction (PMID 8018919)
8

Data Source:
HPRD (in vitro)

		CEACAM3	CEACAM1
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 3	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		Molecular_function Protein Binding Protein Homodimerization Activity
	Biological Process		Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration
Pathways			Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs			Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CEACAM1 CSNK1A1L S100A8 SRC	18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC
Entrez ID		1084	634
HPRD ID		16450	00191
Ensembl ID		ENSG00000170956	ENSG00000079385
Uniprot IDs		G5E978 P40198	P13688 Q3KRG8
PDB IDs			2GK2
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Wound Healing Response To Wounding Peptidyl-serine Phosphorylation Integrin-mediated Signaling Pathway Cell Migration Cell Motility Regulation Of Intrinsic Apoptotic Signaling Pathway Neutrophil Aggregation Cellular Response To Progesterone Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Cell Adhesion Locomotion Sequestering Of Zinc Ion Phagocytosis Positive Regulation Of Integrin Activation Negative Regulation Of Mitochondrial Depolarization Positive Regulation Of Podosome Assembly Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Response To Lipopolysaccharide Regulation Of Podosome Assembly Positive Regulation Of Secretion Response To Molecule Of Bacterial Origin Regulation Of Caveolin-mediated Endocytosis Osteoclast Development Negative Regulation Of Protein Oligomerization Regulation Of Endopeptidase Activity Chemokine Production Sequestering Of Metal Ion Regulation Of Peptidase Activity Regulation Of Integrin Activation Blood Coagulation Hemostasis Regulation Of Early Endosome To Late Endosome Transport Regulation Of Cellular Component Organization Transcytosis Chronic Inflammatory Response Response To Inorganic Substance Signal Complex Assembly Stress Fiber Assembly Cellular Zinc Ion Homeostasis Response To Bacterium Negative Regulation Of Anoikis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Uterus Development	Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle
Tagcloud ?		associating crkl directs engagement engulfment gef guanine immunoreceptor interfere internalization itam knock lamellipodial nap1 nck nck1 nck2 nucleation opsonin ordinate phagocytosis protrusions rac sh2 slp vav wave wave2	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Difference) ?		associating crkl directs engagement engulfment gef guanine immunoreceptor interfere internalization itam knock lamellipodial nap1 nck nck1 nck2 nucleation opsonin ordinate phagocytosis protrusions rac sh2 slp vav wave wave2	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Intersection) ?