SEPT6 and CDC42EP2

Number of citations of the paper that reports this interaction (PMID 11584266)
38

Data Source:
BioGRID (pull down)

		SEPT6	CDC42EP2
Gene Name		septin 6	CDC42 effector protein (Rho GTPase binding) 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Synaptic Vesicle Midbody Cleavage Furrow Axon Terminus	Cytoplasm Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane
	Molecular Function	Protein Binding GTP Binding	Opioid Peptide Activity Rho GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Cytokinesis Viral Process	Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CDC42EP2 CDC42EP3 KDM1A MORN4 PLEKHF2 S100A4 SEPT1 SEPT2 SEPT3 SEPT5 SEPT9 TK1 WHSC1L1	7 interactors: ARHGAP26 CDC42 NME7 RHOQ SEPT6 SEPT7 SNCA
Entrez ID		23157	10435
HPRD ID		06716	09363
Ensembl ID		ENSG00000125354	ENSG00000149798
Uniprot IDs		F5H1J5 Q14141 Q541S4 Q548C9	O14613
PDB IDs		2QAG
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Fetal Process Involved In Parturition Regulation Of Primitive Erythrocyte Differentiation Skeletal Muscle Cell Proliferation Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of L-glutamate Transport Response To Cortisol Thymidine Metabolic Process Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Synaptic Vesicle Targeting Deoxyribonucleoside Monophosphate Biosynthetic Process Histone H3-K4 Demethylation Histone H3-K27 Methylation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage	Organelle Organization Regulation Of Filopodium Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Morphogenesis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Regulation Of Cell Projection Assembly Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament-based Process Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration Positive Regulation Of Transport Regulation Of Cell Shape Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Microtubule-based Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cellular Component Organization Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Membrane Organization Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Organelle Organization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Intracellular Transport Regulation Of Neuron Apoptotic Process Purine Nucleoside Metabolic Process Regulation Of Synaptic Vesicle Recycling
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