TOB2 and CNOT8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TOB2	CNOT8
Gene Name		transducer of ERBB2, 2	CCR4-NOT transcription complex, subunit 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Intracellular Nucleus Cytosol CCR4-NOT Complex
	Molecular Function	Protein Binding Vitamin D Receptor Binding	3'-5'-exoribonuclease Activity Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding
	Biological Process	Female Gamete Generation Negative Regulation Of Cell Proliferation Regulation Of Gene Expression Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Ossification	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Gene Expression Gene Silencing By MiRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Vitiligo ( 22561518)
Protein-Protein Interactions		5 interactors: BHLHE40 CEP76 CNOT7 CNOT8 RPS6KA1	9 interactors: BTG1 BTG2 CNOT1 CNOT2 CNOT3 CNOT4 CNOT6 PRMT1 TOB2
Entrez ID		10766	9337
HPRD ID		09583	07225
Ensembl ID		ENSG00000183864	ENSG00000155508
Uniprot IDs		Q14106	B0AZS3 B7Z8R1 Q9UFF9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MRNA Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Translation Gene Silencing By MiRNA Posttranscriptional Gene Silencing Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Silencing By RNA Posttranscriptional Regulation Of Gene Expression MRNA 3'-end Processing Gene Silencing RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Hepatic Stellate Cell Activation MRNA Catabolic Process RNA Catabolic Process Regulation Of Gene Expression, Epigenetic Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Gene Expression Nucleic Acid Phosphodiester Bond Hydrolysis Cytoplasmic MRNA Processing Body Assembly Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Centriole Replication MRNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Translation In Response To Stress Aromatic Compound Catabolic Process Regulation Of MRNA 3'-end Processing Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Entrainment Of Circadian Clock By Photoperiod Regulation Of Nucleic Acid-templated Transcription MRNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Metabolic Process Photoperiodism Entrainment Of Circadian Clock RNA Processing Regulation Of Protein Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Proliferation Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Centrosome Duplication	Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA 3'-end Processing RNA 3'-end Processing Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Nuclear-transcribed MRNA Catabolic Process Regulation Of Cytoplasmic MRNA Processing Body Assembly MRNA Catabolic Process RNA Catabolic Process Gene Silencing By RNA Regulation Of Translation Gene Silencing Regulation Of Stem Cell Maintenance Positive Regulation Of Organelle Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression MRNA Metabolic Process RNA Processing Regulation Of Cell Differentiation Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Cellular Macromolecule Catabolic Process RNA Phosphodiester Bond Hydrolysis Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Regulation Of Gene Expression Trophectodermal Cell Differentiation Positive Regulation Of MRNA Catabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Gene Expression Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Gene Silencing By MiRNA Blastocyst Formation Posttranscriptional Gene Silencing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Component Biogenesis Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Catabolic Process RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Myeloid Cell Differentiation
Tagcloud ?		angio bioinformatics colony downregulate dramatically erbb2 genesis indicates invasion investigations mechanistic micrornas migration mir mirnas nasopharyngeal negatively np69 npc numerous onco opposite predict promoted providing repressed transducer upregulated upregulation
Tagcloud (Difference) ?		angio bioinformatics colony downregulate dramatically erbb2 genesis indicates invasion investigations mechanistic micrornas migration mir mirnas nasopharyngeal negatively np69 npc numerous onco opposite predict promoted providing repressed transducer upregulated upregulation
Tagcloud (Intersection) ?