TXNRD2 and TADA3

Number of citations of the paper that reports this interaction (PMID 20413580)
3

Data Source:
BioGRID (two hybrid)

		TXNRD2	TADA3
Gene Name		thioredoxin reductase 2	transcriptional adaptor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Intracellular Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Mercury (II) Reductase Activity Mercury Ion Binding Flavin Adenine Dinucleotide Binding NADP Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Protein Domain Specific Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Response To Reactive Oxygen Species Response To Oxygen Radical Cell Redox Homeostasis Detoxification Of Mercury Ion Oxidation-reduction Process	Regulation Of Protein Phosphorylation Chromatin Organization Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Nuclear Division Positive Regulation Of Gene Expression Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation
Pathways		Detoxification of Reactive Oxygen Species	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 22922875)
Protein-Protein Interactions		7 interactors: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3	27 interactors: ADPGK ANKRD12 AR CCDC101 CCNC EIF3J EP300 ESR1 FAM107B HEXIM2 HIST3H3 HSPA8 ING5 KDM1A MAGEH1 NR1I2 PIAS4 RARA RFX1 RXRA SAP18 TADA2A TP53 TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		10587	10474
HPRD ID		18519	04252
Ensembl ID		ENSG00000184470	ENSG00000171148
Uniprot IDs		F5H1L4 F5H2V0 Q9NNW7	A8K899 O75528
PDB IDs		1W1E
Enriched GO Terms of Interacting Partners?		Gene Expression Positive Regulation Of Cellular Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Histone Deacetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Protein Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Acetylation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Internal Peptidyl-lysine Acetylation Chromatin Modification Positive Regulation Of Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Regulation Of Histone Modification Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Protein Acetylation Regulation Of Carbohydrate Metabolic Process CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Chromatin Organization Circadian Rhythm Regulation Of Tubulin Deacetylation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To DNA Damage Stimulus Definitive Erythrocyte Differentiation Regulatory T Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Steroid Hormone Mediated Signaling Pathway Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Chromatin Organization Prostate Gland Development Cellular Response To Steroid Hormone Stimulus Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone Acetylation Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Internal Peptidyl-lysine Acetylation Response To Steroid Hormone
Tagcloud ?			3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb mtmr14 overlap presents prove respect rise seizures srgap3 syndrome terminus typical
Tagcloud (Difference) ?			3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb mtmr14 overlap presents prove respect rise seizures srgap3 syndrome terminus typical
Tagcloud (Intersection) ?