TXNRD2

Gene Name		thioredoxin reductase 2
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Mercury (II) Reductase Activity Mercury Ion Binding Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Response To Reactive Oxygen Species Response To Oxygen Radical Cell Redox Homeostasis Detoxification Of Mercury Ion Oxidation-reduction Process
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 22922875)
Protein-protein Interactions		7 interactors: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3
Entrez ID		10587
HPRD ID		18519
Ensembl ID		ENSG00000184470
Uniprot IDs		F5H1L4 F5H2V0 Q9NNW7
PDB IDs		1W1E
Enriched GO Terms of Interacting Partners?		Gene Expression Positive Regulation Of Cellular Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Histone Deacetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Protein Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Acetylation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Internal Peptidyl-lysine Acetylation Chromatin Modification Positive Regulation Of Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Regulation Of Histone Modification Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Protein Acetylation Regulation Of Carbohydrate Metabolic Process CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Chromatin Organization Circadian Rhythm Regulation Of Tubulin Deacetylation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To DNA Damage Stimulus Definitive Erythrocyte Differentiation Regulatory T Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Transcription From RNA Polymerase II Promoter
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