CEL and LTF

Number of citations of the paper that reports this interaction (PubMedID 3995055)
0

Data Source:
HPRD (in vitro)

		CEL	LTF
Description		carboxyl ester lipase	lactotransferrin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytoplasm Early Endosome Plasma Membrane Cell Surface Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Recycling Endosome Extracellular Exosome Phagocytic Vesicle Lumen Tertiary Granule Lumen
	Molecular Function	Catalytic Activity Sterol Ester Esterase Activity Triacylglycerol Lipase Activity Protein Binding Acetylesterase Activity Heparin Binding Hydrolase Activity Retinyl-palmitate Esterase Activity Carboxylic Ester Hydrolase Activity	Lipopolysaccharide Binding DNA Binding Serine-type Endopeptidase Activity Cysteine-type Endopeptidase Inhibitor Activity Iron Ion Binding Protein Binding Heparin Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding Membrane Destabilizing Activity
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Pancreatic Juice Secretion Intestinal Cholesterol Absorption Retinol Metabolic Process Ceramide Catabolic Process	Ossification Regulation Of Cytokine Production Innate Immune Response In Mucosa Immune System Process Proteolysis Monoatomic Ion Transport Iron Ion Transport Humoral Immune Response Antibacterial Humoral Response Antifungal Humoral Response Killing Of Cells Of Another Organism Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of ATP-dependent Activity Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Host-mediated Suppression Of Viral Proces Negative Regulation Of Viral Genome Replication Innate Immune Response Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Membrane Potential Negative Regulation Of Viral Process Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of NF-kappaB Transcription Factor Activity Cytolysis By Host Of Symbiont Cells Bone Morphogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Bone Mineralization Involved In Bone Maturation Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Positive Regulation Of Chondrocyte Proliferation Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of Osteoclast Development
Pathways		Digestion of dietary lipid Developmental Lineage of Pancreatic Acinar Cells	Mtb iron assimilation by chelation Neutrophil degranulation Metal sequestration by antimicrobial proteins Antimicrobial peptides Amyloid fiber formation
Drugs		Taurocholic acid	3h-Indole-5,6-Diol Lauric acid Nitrilotriacetic acid alpha-D-Fucopyranose Nimesulide (R)-Atenolol Parecoxib
Diseases		Maturity onset diabetes of the young (MODY)
GWAS		Blood protein levels ( 30072576) Early-onset Parkinson's disease ( 28256260) Type 1 diabetes ( 34012112)	AIDS progression ( 21502085) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Early-onset schizophrenia ( 33907183) Inflammatory bowel disease ( 26192919) Macular thickness ( 30535121) Ulcerative colitis ( 26192919)
Interacting Genes		3 interacting genes: BPGM LTF OLR1	13 interacting genes: ACE2 CALM1 CD14 CEL CP EPPIN ITLN1 LCN1 LRP1 LYZ MUC7 UBC USP7
Entrez ID		1056	4057
HPRD ID		07509	01028
Ensembl ID		ENSG00000170835	ENSG00000012223
Uniprot IDs		B4DSX9 O75612 P19835 Q86SR3	B3KSL2 E7ER44 P02788 Q2TUW9 V9HWI4
PDB IDs		1F6W 1JMY 6H0T 6H0V 6H18 6H19 6H1A	1B0L 1BKA 1CB6 1DSN 1EH3 1FCK 1H43 1H44 1H45 1HSE 1L5T 1LCF 1LCT 1LFG 1LFH 1LFI 1LGB 1N76 1SQY 1U62 1VFD 1VFE 1XV4 1XV7 1Z6V 1Z6W 2BJJ 2DP4 2GMC 2GMD 2HD4 2PMS 7JRD 7N88
Enriched GO Terms of Interacting Partners?		Phosphoglycerate Mutase Activity Defense Response Bisphosphoglycerate Mutase Activity Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Positive Regulation Of Bone Mineralization Involved In Bone Maturation Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Phagocytic Vesicle Lumen Membrane Destabilizing Activity Negative Regulation Of Osteoclast Development Intramolecular Phosphotransferase Activity Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development Establishment Of Blood-brain Barrier Negative Regulation Of ATP-dependent Activity Cytolysis By Host Of Symbiont Cells Negative Regulation Of Membrane Potential Specific Granule Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Antifungal Humoral Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Osteoblast Proliferation Neuroinflammatory Response Inflammatory Response Oxygen Transport Host-mediated Suppression Of Viral Proces Low-density Lipoprotein Particle Receptor Activity Innate Immune Response In Mucosa Respiratory Gaseous Exchange By Respiratory System Defense Response To Other Organism Response To Stress Response To Protozoan Erythrocyte Development Defense Response To Protozoan Cysteine-type Endopeptidase Inhibitor Activity Bone Morphogenesis Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Osteoblast Proliferation Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of ATP-dependent Activity Mucosal Immune Response Negative Regulation Of Osteoclast Differentiation Killing By Host Of Symbiont Cells Organ Or Tissue Specific Immune Response Lipoprotein Metabolic Process Lipopolysaccharide Binding Biological Process Involved In Interaction With Symbiont ADP Catabolic Process ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process	Extracellular Region Extracellular Space Endocytic Vesicle Membrane Extracellular Exosome Regulation Of Transport Endocytosis Receptor-mediated Endocytosis Negative Regulation Of Calcium Ion Transport Membrane Raft Opsonin Receptor Activity Oxidoreductase Activity, Acting On Metal Ions, Oxygen As Acceptor Positive Regulation Of Transcytosis Alpha-2 Macroglobulin Receptor Activity Apolipoprotein Receptor Activity Brush Border Membrane Import Into Cell Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Other Organism Diterpenoid Metabolic Process Retinoid Metabolic Process Acetylesterase Activity Oxidoreductase Activity, Acting On Metal Ions Positive Regulation Of Reverse Cholesterol Transport Regulation Of Transcytosis Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Regulation Of Cardiac Muscle Contraction Phagocytosis Cellular Response To Triacyl Bacterial Lipopeptide Response To External Biotic Stimulus Terpenoid Metabolic Process Ceramide Metabolic Process Ferroxidase Activity Lipoprotein Particle Receptor Binding Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Flagellated Sperm Motility Entry Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Monoatomic Ion Transport Regulation Of Striated Muscle Contraction Lipopolysaccharide Receptor Complex Positive Regulation Of Transport Peptidoglycan Immune Receptor Activity Sterol Ester Esterase Activity Isoprenoid Metabolic Process Phospholipid-hydroperoxide Glutathione Peroxidase Activity Astrocyte Activation Involved In Immune Response Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Viral Translation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?