HOXB13 and HOXD4

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXB13	HOXD4
Gene Name		homeobox B13	homeobox D4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex	Nucleus
	Molecular Function	Sequence-specific DNA Binding	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated Epidermis Development Response To Wounding Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 ZNF490	19 interactors: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18
Entrez ID		10481	3233
HPRD ID		05210	00864
Ensembl ID		ENSG00000159184	ENSG00000170166
Uniprot IDs		Q4KR72 Q92826	P09016
PDB IDs		2CRA
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Lens Morphogenesis In Camera-type Eye Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Interleukin-13 Biosynthetic Process Regulation Of Metabolic Process Lens Development In Camera-type Eye Cellular Response To Testosterone Stimulus Positive Regulation Of Interleukin-10 Biosynthetic Process Positive Regulation Of Interleukin-4 Biosynthetic Process Camera-type Eye Morphogenesis Developmental Process Eye Morphogenesis Positive Regulation Of Metabolic Process T-helper 17 Cell Lineage Commitment Olfactory Placode Formation T-helper 17 Cell Differentiation Myeloid Cell Differentiation Organ Morphogenesis Cellular Metabolic Process Lens Induction In Camera-type Eye Cell Fate Commitment T-helper Cell Lineage Commitment Positive Regulation Of Interleukin-2 Biosynthetic Process Multicellular Organismal Development Camera-type Eye Development Megakaryocyte Development	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Tissue Development N-terminal Peptidyl-lysine Acetylation Multicellular Organismal Development Negative Regulation Of Biosynthetic Process Stem Cell Differentiation Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Organ Morphogenesis System Development Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Positive Regulation Of Type I Interferon Production Stem Cell Development N-terminal Protein Amino Acid Acetylation Cell Differentiation
Tagcloud ?		1x10 27x10 assessing carrier country explains familial g84e genotyped geographic gleason hereditary largest missense multiplicatively nccn polygenic prca protect psa rs138213197 snp snps stratifying tnm uk ukgpcs variant varies	allowed canonical confers cos developmentally dnase element embryogenesis embryonal enhancer footprinting heterologous mimic morphogens nevertheless nt2 polyadenylation proper rars reproduces responsive retinoids sequential spatially specifying start temporally transactivated
Tagcloud (Difference) ?		1x10 27x10 assessing carrier country explains familial g84e genotyped geographic gleason hereditary largest missense multiplicatively nccn polygenic prca protect psa rs138213197 snp snps stratifying tnm uk ukgpcs variant varies	allowed canonical confers cos developmentally dnase element embryogenesis embryonal enhancer footprinting heterologous mimic morphogens nevertheless nt2 polyadenylation proper rars reproduces responsive retinoids sequential spatially specifying start temporally transactivated
Tagcloud (Intersection) ?