CACNG3 and AP4M1

Number of citations of the paper that reports this interaction (PMID 14572453)
13

Data Source:
HPRD (two hybrid)

		CACNG3	AP4M1
Gene Name		calcium channel, voltage-dependent, gamma subunit 3	adaptor-related protein complex 4, mu 1 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Endocytic Vesicle Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex	Golgi Trans Cisterna Trans-Golgi Network Coated Pit AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Calcium Channel Activity	Transporter Activity
	Biological Process	Calcium Ion Transport Synaptic Transmission Calcium Ion Transmembrane Transport Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity	Intracellular Protein Transport Golgi To Endosome Transport Vesicle-mediated Transport
Pathways		Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AP4M1 APP	13 interactors: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		10368	9179
HPRD ID		05910	03803
Ensembl ID		ENSG00000006116	ENSG00000221838
Uniprot IDs		O60359	C9JC87 O00189
PDB IDs			3L81
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Golgi To Endosome Transport Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing	Startle Response Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Membrane Depolarization Neuromuscular Process Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Calcium Ion Transmembrane Transport Synaptic Transmission Regulation Of Membrane Potential Regulation Of Synaptic Transmission Calcium Ion Transport Platelet Degranulation Transport Cell-cell Signaling Sensory Perception Of Pain Protein Localization Memory Directional Locomotion Regulation Of Signaling Learning Response To Ethanol Regulation Of Rubidium Ion Transport Ion Transmembrane Transport Regulation Of Endocytosis Platelet Activation Pigment Granule Maturation Endosome To Melanosome Transport Vesicle-mediated Transport Cellular Localization Response To Wounding Monoubiquitinated Protein Deubiquitination Positive Regulation Of Integrin-mediated Signaling Pathway Cellular Pigment Accumulation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Cerebellar Granule Cell Differentiation Negative Regulation Of Cell Cycle G2/M Phase Transition Golgi Vesicle Budding Metal Ion Transport Learning Or Memory Prepulse Inhibition Serotonin Metabolic Process Sleep
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