MPZL2 and MEST

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MPZL2	MEST
Description		myelin protein zero like 2	mesoderm specific transcript
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Catalytic Activity Protein Binding Hydrolase Activity
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Anatomical Structure Morphogenesis Cell-cell Adhesion	Mesoderm Development Regulation Of Lipid Storage Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730 31577861) Lung cancer in ever smokers ( 28604730) Red blood cell count ( 32888494) Sleep duration (long sleep) ( 30846698)	Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: ATF4 MEST MPZL3	23 interacting genes: APP BAG6 BLOC1S2 C6orf47 CD300C CEP70 CIAO2A CIDEB CMTM3 CRELD2 DBN1 FBXO7 FEZ1 FST GAD2 HGS ING5 KIFAP3 LIME1 MPZL2 RNF19B ZNF205 ZNF579
Entrez ID		10205	4232
HPRD ID		05340	06776
Ensembl ID		ENSG00000149573	ENSG00000106484
Uniprot IDs		O60487	A4D1L9 B4DQW6 Q5EB52
PDB IDs
Enriched GO Terms of Interacting Partners?		Lewy Body Core GDF15-GFRAL Signaling Pathway Response To Manganese-induced Endoplasmic Reticulum Stress ATF4-CREB1 Transcription Factor Complex ATF1-ATF4 Transcription Factor Complex Negative Regulation Of Translational Initiation In Response To Stress L-asparagine Metabolic Process Asparagine Metabolic Process CHOP-ATF4 Complex Positive Regulation Of Sodium-dependent Phosphate Transport Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process PERK-mediated Unfolded Protein Response HRI-mediated Signaling Cellular Response To Leucine Starvation Lens Fiber Cell Morphogenesis Regulation Of Phosphate Transport Mitochondrial Respirasome Assembly Response To Manganese Ion Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway CAMP Response Element Binding Protein Binding Cellular Response To Manganese Ion General Transcription Initiation Factor Binding Leucine Zipper Domain Binding Hair Cycle Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Nuclear Periphery Positive Regulation Of Smooth Muscle Cell Apoptotic Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Embryonic Hemopoiesis Dendrite Membrane Positive Regulation Of Vascular Endothelial Growth Factor Production Tissue Development Positive Regulation Of Transcription By RNA Polymerase I Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of Potassium Ion Transport Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway ER-nucleus Signaling Pathway Regulation Of Smooth Muscle Cell Apoptotic Process Integrated Stress Response Signaling	Gamma-tubulin Binding
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