RBM12 and RBM10

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		RBM12	RBM10
Description		RNA binding motif protein 12	RNA binding motif protein 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Nuclear Speck Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Apoptotic Process Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Ribosomal Large Subunit Export From Nucleus
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases			TARP syndrome
GWAS		Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: BRAP GIGYF2 OPTN PRMT2 RBFOX2 RBM10 SNRPB TBC1D4	73 interacting genes: AKAP9 ATN1 BAHD1 BEND7 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 KLF1 MAPRE2 MBD6 MDM2 MEOX2 MIR106B MIR107 MIR128-1 MIR21 MIR214 MIRLET7A1 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I NDEL1 NIN PATZ1 PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12 RBM12B RBM14 RBM4 RBM7 RBMY1F RNF10 SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNRPA SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF275 ZNF317 ZNF408 ZNF473 ZNF526
Entrez ID		10137	8241
HPRD ID		06212	02095
Ensembl ID		ENSG00000244462	ENSG00000182872
Uniprot IDs		Q9NTZ6	A0A0S2Z4W4 A0A0S2Z4X1 P98175
PDB IDs		1WEL 2CPY 2DNN 2EK1 2EK6	2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Cycle G1/S Phase Transition Protein Methylation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone H3R8 Methyltransferase Activity RNA Splicing Regulation Of MRNA Metabolic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Negative Regulation Of Canonical NF-kappaB Signal Transduction Nuclear Progesterone Receptor Binding MRNA Processing U2 SnRNP Binding Macromolecule Methylation Regulation Of MRNA Splicing, Via Spliceosome SnRNP Binding Smooth Muscle Cell Apoptotic Process Negative Regulation Of Signal Transduction Nucleoplasm Protein-arginine Omega-N Asymmetric Methyltransferase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Communication Negative Regulation Of Macromolecule Metabolic Process Methylation Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Signaling MRNA Splicing, Via Spliceosome RNA Binding U7 SnRNP Histone Pre-mRNA DCP Binding 7-methylguanosine Cap Hypermethylation Histone Pre-mRNA 3'end Processing Complex MRNA Metabolic Process U1 SnRNP Binding Regulation Of RNA Splicing Regulation Of Ribosome Biogenesis Regulation Of MRNA Stability Regulation Of MRNA Processing Negative Regulation Of Ribosome Biogenesis Nucleic Acid Binding Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vesicle Fusion Vesicle Positive Regulation Of Xenophagy Negative Regulation Of Receptor Recycling Type 2 Mitophagy Proximal Dendrite Negative Regulation Of Metabolic Process Negative Regulation Of Mitotic Cell Cycle	MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing Nucleic Acid Binding RNA Splicing Regulatory NcRNA-mediated Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RNA Processing Post-transcriptional Gene Silencing Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Base-pairing Post-transcriptional Repressor Activity RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Binding MRNA Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Nuclear Speck Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Ribonucleoprotein Complex Pre-mRNA Binding MRNA 3'-UTR Binding Post-transcriptional Regulation Of Gene Expression U2-type Precatalytic Spliceosome Negative Regulation Of RNA Splicing Microtubule Nucleation
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