TSPAN3 and CLDN11

Number of citations of the paper that reports this interaction (PubMedID 11309411)
64

Data Source:
HPRD (two hybrid, in vivo)

		TSPAN3	CLDN11
Description		tetraspanin 3	claudin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Lipid Droplet Neurofilament Plasma Membrane Bicellular Tight Junction Membrane Cell Junction Axon Basal Part Of Cell Tight Junction Anchoring Junction
	Molecular Function		Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process		Cell Adhesion Spermatogenesis Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Blood glucose levels ( 31928498) Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) ( 28820441) Prostate cancer ( 21743467)
Interacting Genes		7 interacting genes: CLDN11 DRD2 EWSR1 LTB4R2 MC4R RXFP4 SLC13A1	12 interacting genes: AMIGO1 C16orf54 FNDC9 KLRC1 SHISA3 SMIM3 SPINT1 TMEM80 TNFSF14 TSPAN3 TSPAN4 ZP3
Entrez ID		10099	5010
HPRD ID		15512	03207
Ensembl ID		ENSG00000140391	ENSG00000013297
Uniprot IDs		O60637	O75508
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Behavior G Protein-coupled Receptor Activity Regulation Of Feeding Behavior Feeding Behavior Plasma Membrane G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Dopamine Receptor Signaling Pathway RNA Polymerase II, Holoenzyme Transcription Factor TFIIF Complex Melanocyte-stimulating Hormone Receptor Activity Response To Melanocyte-stimulating Hormone Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Neuropeptide Signaling Pathway Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Positive Regulation Of Renal Sodium Excretion Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Locomotion Involved In Locomotory Behavior Melanocortin Receptor Activity Leukotriene Signaling Pathway Keratinocyte Migration Regulation Of Synapse Structural Plasticity Regulation Of Renal Sodium Excretion Interneuron Migration From The Subpallium To The Cortex Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Eating Behavior Secondary Active Sulfate Transmembrane Transporter Activity Galanin Receptor Activity Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Histamine	Membrane
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