ABCF2 and ANKRD28

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		ABCF2	ANKRD28
Description		ATP binding cassette subfamily F member 2	ankyrin repeat domain 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Protein Serine/threonine Phosphatase Complex Lamellipodium Cell Projection
	Molecular Function	Nucleotide Binding ATP Binding ATP Hydrolysis Activity	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process		Positive Regulation Of Focal Adhesion Assembly
Pathways		NFE2L2 regulating MDR associated enzymes	Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Femoral neck bone mineral density ( 22504420) Height ( 31562340) IgG glycosylation ( 23382691) IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391) Pre-treatment viral load in HIV-1 infection ( 31219150)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ANKRD28 HADHA PTEN UPF2	34 interacting genes: ABCF2 AGPAT2 ANK2 ANKRD26 ANKRD50 BCL3 BRCA1 CCDC187 CD164 CSNK2B EEF1G EHMT2 EIF3D GADD45GIP1 HNRNPK HNRNPR INCA1 KCNV2 MYOM1 NOTCH2 NOTCH3 PIBF1 PTRH1 RNF11 TGM2 TGS1 THAP7 TMIE TNKS TNKS2 TTN UACA YTHDC1 ZNF512B
Entrez ID		10061	23243
HPRD ID		12403	10651
Ensembl ID		ENSG00000033050	ENSG00000206560
Uniprot IDs		A0A090N7X1 Q9UG63	O15084
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell-substrate Junction Organization Regulation Of Focal Adhesion Assembly Lipid Modification Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Regulation Of Cell-matrix Adhesion Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Acetyl-CoA C-acetyltransferase Activity Glycerophospholipid Metabolic Process (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Cardiolipin Acyl-chain Remodeling Regulation Of Cell Junction Assembly Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Synaptic Vesicle Clustering Regulation Of Cell-substrate Adhesion Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Phospholipid Metabolic Process Cardiolipin Metabolic Process Glycerolipid Metabolic Process Enoyl-CoA Hydratase Activity 3-hydroxyacyl-CoA Dehydratase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Presynaptic Membrane Organization Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Presynaptic Membrane Assembly Protein Serine/threonine Phosphatase Complex Locomotor Rhythm Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential Maternal Behavior Long-chain Fatty Acyl-CoA Hydrolase Activity Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Meiotic Spindle Assembly	M Band Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Telomere Capping Glomerular Capillary Formation Enzyme Binding Marginal Zone B Cell Differentiation Negative Regulation Of Macromolecule Metabolic Process Heterochromatin Formation Cellular Response To Cocaine Protein Localization To Chromosome, Telomeric Region Protein Auto-ADP-ribosylation Protein Kinase A Signaling NAD+-protein-glutamate ADP-ribosyltransferase Activity Random Inactivation Of X Chromosome NAD+-protein-aspartate ADP-ribosyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Regulation Of Telomere Capping C2H2 Zinc Finger Domain Binding Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Kinase Regulator Activity Regulation Of MiRNA Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Poly-ADP-ribosylation Negative Regulation Of Fatty Acid Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-threonine Phosphorylation NAD+-protein Mono-ADP-ribosyltransferase Activity Pericentriolar Material Positive Regulation Of Telomere Maintenance Via Telomerase Nucleus Positive Regulation Of Telomere Maintenance Via Telomere Lengthening NAD+ Poly-ADP-ribosyltransferase Activity Negative Regulation Of Receptor Signaling Pathway Via STAT Mature B Cell Differentiation Involved In Immune Response Protein Localization To T-tubule Nucleoplasm Bcl3-Bcl10 Complex Mature B Cell Differentiation Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
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