GPR61 and ARLN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR61	ARLN
Description		G protein-coupled receptor 61	allregulin
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Endosome Membrane Membrane Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Ligand-independent Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		20 interacting genes: APP ARL6IP6 ARLN ATP6V0B CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1	73 interacting genes: ADGRG3 AQP2 AQP6 ARL13B ATP2A2 BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 EBP ELN ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 GPX8 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PLN PTGES REEP4 RETREG3 RHBDL1 RHCG SCN3B SERINC2 SHISAL1 SLC10A6 SLC14A2 SLC19A3 SLC35E3 SLC35H1 SLC39A2 SLC41A3 SLC71A2 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A
Entrez ID		83873	401152
HPRD ID		06077	14223
Ensembl ID		ENSG00000156097	ENSG00000164096
Uniprot IDs		G4XH66 Q9BZJ8	Q8WVX3
PDB IDs		8KGK 8TB0 8TB7
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Gap Junction-mediated Intercellular Transport Cell-cell Signaling Signaling Bleb Assembly Intercellular Transport Cell Communication Transmembrane Transport Connexin Complex Gap Junction Channel Activity Chemical Synaptic Transmission Protein Localization To Membrane Gap Junction Trans-synaptic Signaling Synaptic Signaling	Membrane Transmembrane Transport Protein Binding Plasma Membrane Calcium Ion-transporting ATPase Complex Endoplasmic Reticulum Membrane G Protein-coupled Receptor Activity Connexin Complex Regulation Of Heart Rate Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity One-carbon Compound Transport Carbon Dioxide Transmembrane Transport Gap Junction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Transporter Inhibitor Activity SA Node Cell Action Potential Transmembrane Transporter Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Cardiac Muscle Cell Membrane Potential Autophagosome Membrane Docking Regulation Of Cardiac Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Renal Water Transport Regulation Of System Process Ammonium Channel Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Ammonium Transmembrane Transport Regulation Of Blood Circulation Calcium-mediated Signaling Metal Ion Transport Regulation Of Striated Muscle Contraction
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