JPH1 and EMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		JPH1	EMP1
Description		junctophilin 1	epithelial membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex Sarcoplasmic Reticulum Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle	Protein Binding
	Biological Process	Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Calcium Ion Transport Into Cytosol	Apoptotic Process Epidermis Development Bleb Assembly
Pathways
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) Uterine fibroids ( 28836065)	Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 28869591 30598549) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin levels ( 29403010)
Interacting Genes		17 interacting genes: AQP6 EDDM3B EMP1 GPR42 HTATIP2 LEPROTL1 MEOX2 NAT8 PLP1 RSPH1 SLC16A13 STRIT1 TMEM120B TMEM65 TTN UACA UBC	61 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 CATSPERH CCR5 CD37 CD3G CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM31 TMEM9 TSPO2
Entrez ID		56704	2012
HPRD ID		07286	11892
Ensembl ID		ENSG00000104369	ENSG00000134531
Uniprot IDs		Q86VR1 Q9HDC5	P54849
PDB IDs		7RW4
Enriched GO Terms of Interacting Partners?			Membrane Plasma Membrane Protein Binding G Protein-coupled Receptor Activity External Side Of Plasma Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Multivesicular Body Membrane
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