WASH1 and KIAA1033

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (affinity chromatography technology, two hybrid, biochemical)

		WASH1	KIAA1033
Gene Name		WAS protein family homolog 1	KIAA1033
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Early Endosome Early Endosome Membrane Recycling Endosome Recycling Endosome Membrane WASH Complex Invadopodium	Nucleoplasm Endosome BLOC-1 Complex WASH Complex
	Molecular Function	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding
	Biological Process	Exocytosis Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Retrograde Transport, Endosome To Plasma Membrane	Endosome Organization Endosomal Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BECN1 BLOC1S2 KIAA0196 KIAA1033 RNF2	2 interactors: SMAD2 WASH1
Entrez ID		100287171	23325
HPRD ID			13829
Ensembl ID			ENSG00000136051
Uniprot IDs		A8K0Z3	Q2M389
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosomal Transport Intracellular Transport Cellular Response To Aluminum Ion Establishment Of Localization In Cell Positive Regulation Of Mitochondrion Degradation CVT Pathway Histone H2A-K119 Monoubiquitination Cellular Localization Response To Aluminum Ion Late Endosome To Vacuole Transport Organelle Organization Regulation Of Mitochondrion Degradation Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Histone H2A Monoubiquitination Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Macroautophagy Histone H2A Ubiquitination Endomembrane System Organization Cellular Response To Nitrogen Starvation Positive Regulation Of Mitochondrial Membrane Permeability Response To Vitamin E Histone Monoubiquitination Anterograde Synaptic Vesicle Transport Nucleophagy Beta-amyloid Metabolic Process Microtubule Nucleation Melanosome Organization Protein Targeting To Vacuole Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Epidermal Growth Factor Stimulus Establishment Of Protein Localization To Vacuole Microtubule Polymerization Anterograde Axon Cargo Transport Response To Epidermal Growth Factor Endosome Organization Histone Ubiquitination Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Autophagy Regulation Of Membrane Permeability Transport Secretory Granule Organization Protein Monoubiquitination Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Autophagic Vacuole Assembly Axon Cargo Transport Cellular Defense Response Lysosome Organization	Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Primary MiRNA Processing Positive Regulation Of Mesoderm Development Secretion By Cell Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Secretion Retrograde Transport, Endosome To Plasma Membrane SMAD Protein Complex Assembly Positive Regulation Of Pseudopodium Assembly Paraxial Mesoderm Morphogenesis Nodal Signaling Pathway Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis Regulation Of Activin Receptor Signaling Pathway Paraxial Mesoderm Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Positive Regulation Of Epithelial To Mesenchymal Transition Activin Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of BMP Signaling Pathway Insulin Secretion Posttranscriptional Gene Silencing Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Stem Cell Differentiation Endoderm Formation Embryonic Axis Specification SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Actin Nucleation Embryonic Cranial Skeleton Morphogenesis Gene Silencing By RNA Peptide Hormone Secretion Peptide Secretion Digestive Tract Morphogenesis Retrograde Transport, Endosome To Golgi Somatic Stem Cell Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To DsRNA Regulation Of Cellular Component Organization Endoderm Development Regulation Of BMP Signaling Pathway
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Tagcloud (Difference) ?			ad americans arabs cargo caucasian cleave cognitively elders endocytic endocytosis endosome formally implicate israeli neurotoxic physiologically proteolytic rab7a replicated retrieval retromer secretases snps snx1 snx3 sorl1 sorting suggestion vegas
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