PIGK and GPAA1

Number of citations of the paper that reports this interaction (PubMedID 10793132)
43

Data Source:
HPRD (in vitro, in vivo)

		PIGK	GPAA1
Description		phosphatidylinositol glycan anchor biosynthesis class K	glycosylphosphatidylinositol anchor attachment 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Peptidase Activity Transferase Activity GPI Anchor Binding	GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding
	Biological Process	GPI Anchor Biosynthetic Process Proteolysis Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis	GPI Anchor Biosynthetic Process Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways		Attachment of GPI anchor to uPAR	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Chronotype ( 27494321 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Type 2 diabetes (age of onset) ( 28060188)	Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: ALPP GPAA1 PIGT	10 interacting genes: AGTR1 AQP2 EIF3E GNRHR GRIK5 PIGK PIGT PIGU PIN1 PRR13
Entrez ID		10026	8733
HPRD ID		05474	04334
Ensembl ID		ENSG00000142892	ENSG00000197858
Uniprot IDs		Q92643	O43292
PDB IDs		7W72 7WLD 8IMX 8IMY	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		GPI-anchor Transamidase Complex Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis GPI Anchor Binding GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Glycerophospholipid Biosynthetic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process GPI-anchor Transamidase Activity Glycerophospholipid Metabolic Process Alkaline Phosphatase Activity Protein Maturation Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Carbohydrate Derivative Biosynthetic Process Lipid Biosynthetic Process Organophosphate Biosynthetic Process Carbohydrate Derivative Metabolic Process Maintenance Of Protein Localization In Organelle Organophosphate Metabolic Process Maintenance Of Protein Location In Cell Maintenance Of Protein Location Endoplasmic Reticulum Membrane Lipid Metabolic Process Maintenance Of Location In Cell Phosphatase Activity Maintenance Of Location Phosphate-containing Compound Metabolic Process Neuron Apoptotic Process Side Of Membrane Endoplasmic Reticulum	GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI-anchor Transamidase Activity GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Glycerolipid Metabolic Process Phosphatidylinositol Metabolic Process Gamma-tubulin Binding Glycerophospholipid Biosynthetic Process Angiotensin Type I Receptor Activity Cis-trans Isomerase Activity Negative Regulation Of ARF Protein Signal Transduction Membrane Lipid Metabolic Process
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