PIGK and ALPP

Number of citations of the paper that reports this interaction (PMID 11278620)
9

Data Source:
HPRD (in vivo, in vitro)

		PIGK	ALPP
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class K	alkaline phosphatase, placental
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane GPI-anchor Transamidase Complex	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Protein Disulfide Isomerase Activity GPI-anchor Transamidase Activity Cysteine-type Endopeptidase Activity Protein Binding GPI Anchor Binding	Magnesium Ion Binding Alkaline Phosphatase Activity Zinc Ion Binding
	Biological Process	Protein Folding C-terminal Protein Lipidation Proteolysis Attachment Of GPI Anchor To Protein Post-translational Protein Modification Cellular Protein Metabolic Process	Dephosphorylation
Pathways		Post-translational protein modification Attachment of GPI anchor to uPAR Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Height ( 19570815)
Protein-Protein Interactions		3 interactors: ALPP GPAA1 PIGT	7 interactors: ALPPL2 GPLD1 KRTAP10-3 KRTAP4-12 KRTAP5-9 LATS1 PIGK
Entrez ID		10026	250
HPRD ID		05474	01379
Ensembl ID		ENSG00000142892	ENSG00000163283
Uniprot IDs		B4E2M3 Q92643	P05187
PDB IDs			1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?		Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Lipid Biosynthetic Process Phosphate-containing Compound Metabolic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Neuron Apoptotic Process Neuron Death Lipid Metabolic Process Protein Localization To Endoplasmic Reticulum Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell	GPI Anchor Metabolic Process GPI Anchor Release Cellular Response To Triglyceride Glycolipid Metabolic Process Positive Regulation Of High-density Lipoprotein Particle Clearance Hematopoietic Stem Cell Migration To Bone Marrow Hematopoietic Stem Cell Migration Positive Regulation Of Cytolysis Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Negative Regulation Of Triglyceride Catabolic Process Complement Receptor Mediated Signaling Pathway Phosphate-containing Compound Metabolic Process Epidermis Development Response To Triglyceride Glycerophospholipid Metabolic Process Attachment Of GPI Anchor To Protein Glycerolipid Metabolic Process Phospholipid Metabolic Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Transepithelial Transport Cellular Response To PH Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Alkaline Phosphatase Activity Cellular Response To Cholesterol Tissue Development Cellular Response To Sterol Regulation Of Triglyceride Biosynthetic Process Cell Migration Involved In Sprouting Angiogenesis Response To Cholesterol Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Lipid Catabolic Process Cytoplasmic Sequestering Of Protein Hippo Signaling Cellular Response To Hormone Stimulus C-terminal Protein Lipidation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Protein Transport Positive Regulation Of Phosphatase Activity Blood Vessel Endothelial Cell Migration Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Establishment Of Protein Localization Response To PH
Tagcloud ?			adsc adscs buffered capacities coinjection encapsulated ganglia glycolic intramuscularly lactic leak masson microspheres nerves ngf pbs periurethral plga pnt pudendal reassessed retrograde rupp sui transection trichrome trk urethra urodynamic
Tagcloud (Difference) ?			adsc adscs buffered capacities coinjection encapsulated ganglia glycolic intramuscularly lactic leak masson microspheres nerves ngf pbs periurethral plga pnt pudendal reassessed retrograde rupp sui transection trichrome trk urethra urodynamic
Tagcloud (Intersection) ?