KCNJ18 and EMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCNJ18	EMD
Description		potassium inwardly rectifying channel subfamily J member 18	emerin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane Monoatomic Ion Channel Complex	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation
Pathways			Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Thyrotoxic hypokalemic periodic paralysis (TPP)	Emery-Dreifuss muscular dystrophy
GWAS		Body mass index ( 26426971)	Mean spheric corpuscular volume ( 32888494)
Interacting Genes		2 interacting genes: EMD KCNJ2	100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774
Entrez ID		100134444	2010
HPRD ID			02309
Ensembl ID		ENSG00000260458	ENSG00000102119
Uniprot IDs		B7U540	P50402
PDB IDs			1JEI 2ODC 2ODG 6GHD 6RPR 7NDY
Enriched GO Terms of Interacting Partners?		Muscle System Process TMEM240-body Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Relaxation Of Skeletal Muscle Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Positive Regulation Of Transport Spindle Pole Centrosome Positive Regulation Of Protein Export From Nucleus Cortical Endoplasmic Reticulum Magnesium Ion Transport Membrane Repolarization During Action Potential Relaxation Of Muscle Membrane Depolarization During Cardiac Muscle Cell Action Potential Inward Rectifier Potassium Channel Activity Regulation Of Resting Membrane Potential Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Skeletal Muscle Contraction Relaxation Of Cardiac Muscle Membrane Depolarization During Action Potential Intracellular Potassium Ion Homeostasis Regulation Of Protein Export From Nucleus Amyloid Fibril Formation Nuclear Outer Membrane Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Potassium Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Regulation Of Membrane Repolarization Membrane Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Potassium Ion Homeostasis Beta-tubulin Binding Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Potassium Ion Import Across Plasma Membrane T-tubule Intercalated Disc Nuclear Membrane Organization Nuclear Inner Membrane Cardiac Conduction Membrane Depolarization Skeletal Muscle Cell Differentiation Positive Regulation Of Nucleocytoplasmic Transport System Process Protein Homotetramerization Regulation Of Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Transport Cellular Response To Mechanical Stimulus Phosphatidylinositol-4,5-bisphosphate Binding	Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway
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