GDF15

Gene Name		growth differentiation factor 15
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity
	Biological Process	Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cell Development SMAD Protein Signal Transduction Positive Regulation Of Myoblast Fusion
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MAPK14 MDFI
Entrez ID		9518
HPRD ID		05608
Ensembl ID		ENSG00000130513
Uniprot IDs		Q99988
PDB IDs
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of Protein Import Into Nucleus Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of MAP Kinase Activity P38MAPK Cascade Regulation Of Nucleocytoplasmic Transport MAPK Cascade Regulation Of Intracellular Protein Transport Activation Of Protein Kinase Activity Skeletal System Morphogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Wnt Signaling Pathway Regulation Of Intracellular Transport Positive Regulation Of MAPK Cascade Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Brown Fat Cell Differentiation Skeletal System Development Positive Regulation Of Transferase Activity Regulation Of MAPK Cascade Regulation Of Protein Transport 3'-UTR-mediated MRNA Stabilization Regulation Of Establishment Of Protein Localization Stress-induced Premature Senescence Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Myoblast Differentiation Trophoblast Giant Cell Differentiation Positive Regulation Of Myoblast Fusion Positive Regulation Of Protein Modification Process Response To Muramyl Dipeptide Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Organ Morphogenesis Regulation Of Cellular Localization Cartilage Condensation
Tagcloud ?		a2780 a2780cis abrogated allowing alter appropriate basal bearing carboplatin colony comparing interestingly knockdown lobular microarrays necrotic ovarian p16 p27 parental platinum poorly resistance serve shrna suppressing transduced variant