MKKS

Gene Name		McKusick-Kaufman syndrome
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Centrosome Cytosol Motile Cilium
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding ATP Binding Unfolded Protein Binding
	Biological Process	Heart Looping Protein Folding Spermatid Development Determination Of Left/right Symmetry Heart Development Visual Perception Sensory Perception Of Smell Gonad Development Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Melanosome Transport Nonmotile Primary Cilium Assembly Social Behavior Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Multicellular Organism Growth Vasodilation Cilium Assembly Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Blood Pressure Intracellular Transport Brain Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Chaperone-mediated Protein Complex Assembly Cartilage Development Pigment Granule Aggregation In Cell Center Convergent Extension Involved In Gastrulation Cilium Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: APP PTN
Entrez ID		8195
HPRD ID		05356
Ensembl ID		ENSG00000125863
Uniprot IDs		B7Z3W9 Q9NPJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Learning Learning Or Memory Cognition Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Single-organism Behavior Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Behavior Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Remodeling Negative Regulation Of Catalytic Activity Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neurological System Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Bone Mineralization Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Biomineral Tissue Development Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning
Tagcloud ?		already bioavailable catalysis chance continuously cot drugable erk2 extensively granulocytes ikks iraks jnks keep kinases kinome lymphoytes mapks meks mk2 mnk1 opening overview seem selectivity summarise tak1 toll tpl