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CLPP

Name caseinolytic mitochondrial matrix peptidase proteolytic subunit
Structure PDB 1TG6
Novel Interactors 2 novel interactors: STAT4 TNFSF9
Interactors 17 interactors: ABI2 C14orf119 CHCHD3 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
  • Endopeptidase Clp Complex
Molecular Function
  • Endopeptidase Activity
  • ATP-dependent Peptidase Activity
  • Serine-type Endopeptidase Activity
  • Protein Binding
  • Peptidase Activity
  • Serine-type Peptidase Activity
  • Hydrolase Activity
  • Identical Protein Binding
  • ATPase Binding
Biological Process
  • Proteolysis
  • Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
  • Membrane Protein Proteolysis
  • Mitochondrial Protein Catabolic Process
  • Proteolysis Involved In Protein Catabolic Process
Pathways
  • Mitochondrial protein degradation
Drugs
  • N-Formylmethionine
GWAS No GWAS studies recorded
Entrez ID 8192
HPRD ID 03074
Ensembl ID ENSG00000125656
Uniprot IDs Q16740
PDB IDs 1TG6 6BBA 6DL7 6H23 7UVM 7UVN 7UVR 7UVU 7UW0 7VP9 7WH5 8HGK 8I7X 8W7C 8W7E 8WUZ 8YLB

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