SNX27

Description		sorting nexin 27
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GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Endosome Early Endosome Cytosol Membrane Retromer Complex Early Endosome Membrane WASH Complex Schaffer Collateral - CA1 Synapse Postsynapse Postsynaptic Recycling Endosome Postsynaptic Early Endosome Glutamatergic Synapse
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding
	Biological Process	Establishment Of Natural Killer Cell Polarity Intracellular Protein Transport Signal Transduction Endosome To Lysosome Transport Protein Transport Endosomal Transport Endocytic Recycling Regulation Of Synapse Maturation Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		16 interacting genes: ACE2 ACVR2B APP BRSK2 CDK16 DGKZ ERBB4 HLCS PDGFRB PNPLA3 PTEN RPS6KA1 SELP SUMO2 UBC VANGL2
Entrez ID		81609
HPRD ID		11591
Ensembl ID		ENSG00000143376
Uniprot IDs		A0A2R8Y8A7 Q96L92
PDB IDs		4HAS 5ZN9 6SAK 7CT1 7E0B 7P72 7PCB 8TTT 8TTU 8TTV
Enriched GO Terms of Interacting Partners?		Kinase Activity Protein Metabolic Process Phosphorylation Regulation Of Cell Communication Protein Kinase Activity Regulation Of Signaling Protein Modification Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cell Migration Phosphate-containing Compound Metabolic Process Protein Phosphorylation Regulation Of Synaptic Vesicle Clustering ATP Binding Cell Motility Receptor Complex Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Nucleotide Binding Transferase Activity Regulation Of Signal Transduction Retina Vasculature Development In Camera-type Eye Protein Tag Activity Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Macromolecule Metabolic Process Response To Growth Factor Anatomical Structure Morphogenesis Establishment Of Planar Polarity System Development Regulation Of Reactive Oxygen Species Metabolic Process Phosphatidic Acid Biosynthetic Process Protein Serine/threonine/tyrosine Kinase Activity Apical Plasma Membrane Regulation Of Smooth Muscle Cell Proliferation Axonogenesis Protein Serine/threonine Kinase Activity Enzyme Binding Positive Regulation Of Excitatory Postsynaptic Potential Reproductive Behavior Phosphatidic Acid Metabolic Process Plasma Membrane Glycerophospholipid Biosynthetic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Proteolysis Amyloid-beta Complex Regulation Of Cellular Component Organization Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion
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