SLA

Name	Src like adaptor
Structure
Interactors	22 interactors: ABI2 BLK CBL CD247 EGFR EPHA2 ERBB2 ERBB3 ERBB4 FGFR1 FLT3 GAB1 GSK3B LAT MYO15B PAFAH1B2 PTK6 QARS1 SYK UBE4A VAV1 ZAP70
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane COP9 Signalosome
	Molecular Function	Phosphotyrosine Residue Binding Epidermal Growth Factor Receptor Binding Protein Binding
	Biological Process	Signal Transduction Regulation Of MAPK Cascade
Pathways	Negative regulation of FLT3
GWAS	Bone erosion in rheumatoid arthritis ( 28512992 ) Brain morphology (MOSTest) ( 32665545 ) Eosinophil percentage of white cells ( 32888494 ) Graves' disease ( 23612905 ) Multiple sclerosis ( 31604244 ) Temperament ( 22832960 ) Vitiligo ( 22561518 27723757 )
Entrez ID	6503
HPRD ID	03060
Ensembl ID	ENSG00000155926
Uniprot IDs	Q13239
PDB IDs	2CUD
GO Terms Enriched among Interactors ?	Peptidyl-tyrosine Phosphorylation Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Protein Kinase Activity Cell Surface Receptor Signaling Pathway Kinase Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Phosphorylation Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERBB2 Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling ERBB Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction ATP Binding Transferase Activity Positive Regulation Of MAPK Cascade Cell Migration Receptor Complex Regulation Of Cell Communication Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway Cell Motility Nucleotide Binding Regulation Of Signal Transduction Signal Transduction Intracellular Signal Transduction Intracellular Signaling Cassette Protein Modification Process Phosphate-containing Compound Metabolic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Positive Regulation Of Protein Modification Process Growth Factor Binding Phosphotyrosine Residue Binding Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Protein Autophosphorylation Immune Response-activating Cell Surface Receptor Signaling Pathway Developmental Process Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Regulation Of Protein Modification Process Plasma Membrane Cell Differentiation